Study of Treatable Traits in Various Chronic Obstructive Airways Diseases Including COPD, Asthma, Bronchiectasis, Cystic Fibrosis, and Primary Ciliary Dyskinesia

What this Trial Is About

Respiratory diseases affect one in five people worldwide and are a leading cause of illness and death. This study focuses on chronic obstructive airways diseases, including chronic obstructive pulmonary disease COPD, asthma, bronchiectasis, cystic fibrosis, and primary ciliary dyskinesia. Researchers aim to compare lung function and other disease effects across these conditions and explore how specific treatable traits relate to physical activity and quality of life. Participants will undergo pulmonary function testing to assess large and small airway involvement, exercise capacity, physical activity, and body composition. The study includes people with different airway diseases as well as healthy controls. The study is observational and does not involve treatment but collects detailed physiological and health data. During the study, participants physical activity will be monitored over a 7-day period as the primary outcome. Assessments include lung function tests and exercise evaluations, along with measurements of body composition. Researchers will also collect information on health-related quality of life and other disease-specific traits. The study is led by the University of Leeds and includes adults aged 18 to 65 years.

Evaluating Treatable Traits Across the Spectrum of Chronic Obstructive Airways Disease