Actively Recruiting
Advancing Dupuytren's Contracture Treatment: a Clinical Prospective Study on Ultrasound-Guided Needle Knife Dissection
Led by Mohamed Maher Ismail Ahmed Elashmawy · Updated on 2025-01-27
30
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dupuytren's contracture is a condition that causes progressive thickening and tightening of the tissue in the palm, leading to hand deformity and difficulty moving the fingers. This research aims to study the use of a minimally invasive procedure called ultrasound-guided needle knife dissection to treat this condition. The study focuses on improving hand movement and patient satisfaction while reducing complications compared to traditional surgical methods. Participants will receive the ultrasound-guided needle knife dissection, where a small blade is guided by ultrasound imaging to carefully cut the fibrous cords causing the contracture. Local anesthesia with lidocaine and bupivacaine will be used for comfort during the procedure. The device used is a Sonosite M-Turbo ultrasound machine with a linear probe for real-time imaging to ensure precise and safe treatment. During the study, participants’ hand function and mobility will be assessed over six months to measure improvement. Researchers will also collect patient feedback on satisfaction and monitor for any complications related to the procedure. The study includes follow-up visits to evaluate results and safety, lasting a total of six months after treatment.
CONDITIONS
Brief Title
Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants diagnosed with Dupuytren's Contracture.
- Willing to undergo ultrasound-guided needle knife dissection.
- Age 18 years or older.
You will not qualify if you...
- Previous surgery or needle aponeurotomy for Dupuytren's Contracture on the same hand.
- Active hand infections, open wounds, or skin conditions in the treatment area.
- Coagulopathy or use of anticoagulants that cannot be safely paused.
- Neuromuscular disorders affecting hand function.
- Pregnancy or breastfeeding.
- Uncontrolled systemic illnesses like poorly managed diabetes or cardiovascular disease.
- Known allergy to local anesthetics.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single procedure with immediate recovery
Participants undergo ultrasound-guided needle knife dissection, a minimally invasive procedure using local anesthesia to treat Dupuytren's Contracture and improve hand function.
1 procedure visit (in-person)
Duration - 6 months
Participants are monitored for hand mobility improvement, patient satisfaction, and any procedure-related complications.
Periodic follow-up visits during 6 months
Trial Site Locations
Total: 1 location
1
Mansoura University Hospital
Al Mansurah, Dakahlia Governorate, Egypt, 35516
Actively Recruiting
Research Team
M
Mohamed Maher Elashmawy, MD, PHD.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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