Actively Recruiting
Evaluating Ultrasound-Guided Needle Knife Dissection for Dupuytren's Contracture A Prospective Clinical Study on Hand Function and Safety
Led by Mohamed Maher Ismail Ahmed Elashmawy · Updated on 2025-01-27
30
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dupuytren's contracture is a condition that causes progressive thickening and tightening of the tissue in the palm, leading to hand deformity and loss of function. Researchers are investigating a minimally invasive treatment called ultrasound-guided needle knife dissection to improve hand movement and reduce complications compared to traditional surgery. This study focuses on evaluating hand mobility and patient satisfaction over a six-month period following the procedure. The treatment involves using a needle knife under ultrasound guidance to carefully cut the fibrous cords causing the contracture. Local anesthesia with lidocaine and bupivacaine is used to ensure patient comfort during the procedure. Real-time imaging with a Sonosite M-Turbo Ultrasound Machine helps provide precise dissection. The study aims to assess the safety and effectiveness of this technique in improving hand function while minimizing risks. Participants will be monitored for changes in hand mobility and overall hand function over six months after treatment. Researchers will also collect patient-reported satisfaction and track any complications during this follow-up period. The study includes detailed assessments to measure improvements and ensure safety throughout the study duration.
CONDITIONS
Official Title
Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with Dupuytren's Contracture
- Willing to undergo ultrasound-guided needle knife dissection
You will not qualify if you...
- Previous surgery or needle aponeurotomy for Dupuytren's Contracture on the same hand
- Active hand infections, open wounds, or skin conditions in the treatment area
- Coagulopathy or use of anticoagulants that cannot be safely paused
- Neuromuscular disorders affecting hand function
- Pregnancy or breastfeeding
- Uncontrolled systemic illnesses such as poorly managed diabetes or cardiovascular disease
- Known allergy to local anesthetics
AI-Screening
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Trial Site Locations
Total: 1 location
1
Mansoura University Hospital
Al Mansurah, Dakahlia Governorate, Egypt, 35516
Actively Recruiting
Research Team
M
Mohamed Maher Elashmawy, MD, PHD.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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