Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06788847

Evaluating Ultrasound-Guided Needle Knife Dissection for Dupuytren's Contracture A Prospective Clinical Study on Hand Function and Safety

Led by Mohamed Maher Ismail Ahmed Elashmawy · Updated on 2025-01-27

30

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Dupuytren's contracture is a condition that causes progressive thickening and tightening of the tissue in the palm, leading to hand deformity and loss of function. Researchers are investigating a minimally invasive treatment called ultrasound-guided needle knife dissection to improve hand movement and reduce complications compared to traditional surgery. This study focuses on evaluating hand mobility and patient satisfaction over a six-month period following the procedure. The treatment involves using a needle knife under ultrasound guidance to carefully cut the fibrous cords causing the contracture. Local anesthesia with lidocaine and bupivacaine is used to ensure patient comfort during the procedure. Real-time imaging with a Sonosite M-Turbo Ultrasound Machine helps provide precise dissection. The study aims to assess the safety and effectiveness of this technique in improving hand function while minimizing risks. Participants will be monitored for changes in hand mobility and overall hand function over six months after treatment. Researchers will also collect patient-reported satisfaction and track any complications during this follow-up period. The study includes detailed assessments to measure improvements and ensure safety throughout the study duration.

CONDITIONS

Official Title

Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with Dupuytren's Contracture
  • Willing to undergo ultrasound-guided needle knife dissection
Not Eligible

You will not qualify if you...

  • Previous surgery or needle aponeurotomy for Dupuytren's Contracture on the same hand
  • Active hand infections, open wounds, or skin conditions in the treatment area
  • Coagulopathy or use of anticoagulants that cannot be safely paused
  • Neuromuscular disorders affecting hand function
  • Pregnancy or breastfeeding
  • Uncontrolled systemic illnesses such as poorly managed diabetes or cardiovascular disease
  • Known allergy to local anesthetics

AI-Screening

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Trial Site Locations

Total: 1 location

1

Mansoura University Hospital

Al Mansurah, Dakahlia Governorate, Egypt, 35516

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Research Team

M

Mohamed Maher Elashmawy, MD, PHD.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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