Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06577311

Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)

Led by The Center for Clinical and Cosmetic Research · Updated on 2024-08-29

20

Participants Needed

1

Research Sites

50 weeks

Total Duration

On this page

Sponsors

T

The Center for Clinical and Cosmetic Research

Lead Sponsor

B

Biofrontera Inc.

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to test how safe and effective it is to treat early form of cancer cells found in the upper skin layer of the face, using a light-sensitive gel used in combination with a light source. The main questions this trial aims to answer are: * to confirm using laboratory testing, how much of the affected facial skin cancer section the treatment was able to remove, and; * seeing how many participants had no remaining affected facial skin cancer sections after treatment. Participants who qualify will be asked to complete 14 visits in total and will receive a total of two treatments, after voluntarily consent has been given.

CONDITIONS

Official Title

Evaluating the Use of Photodynamic Therapy to Treat Facial Cutaneous Squamous Cell Carcinoma in Situ (SCCis)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Must be an adult (18 years of age or older)
  • Must have a recently diagnosed (no more than six months from first study visit) facial SCCis lesion that meets surgery excision size requirements
  • Cannot have other dermatological disease in the SCCis target area
  • Must be willing to follow study instructions and complete study requirements, including not using non-approved lotions and creams on the treatments areas
  • Voluntary written consent required
  • Allow photographs of the area of skin cancer being treated on the face
  • Agree to use acceptable forms of birth control. If female, cannot be pregnant before and during the study
Not Eligible

You will not qualify if you...

  • Pregnant or lactating
  • Sensitive to any of the study treatment ingredients
  • Medical laboratory evidence of other non-SCCis tumor in the target lesion biopsy specimen
  • History of recurrence if the target SCCis lesion
  • Evidence of dermatological disease or skin condition in the treatment area
  • Medical laboratory evidence of growth patterns in the target lesion biopsy specimen
  • Chronic medical condition that in the Investigators opinion will interfere in the trial or affect participant safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Center for Clinical and Cosmetic Research

Aventura, Florida, United States, 33180

Actively Recruiting

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Research Team

C

Clinical Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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