Actively Recruiting
Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea
Led by Wright State University · Updated on 2026-02-18
48
Participants Needed
1
Research Sites
248 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Rosacea is a common skin condition associated with easy blushing and red face; many patients with rosacea react to sunlight with increased redness. The purpose of this study is to determine if the use of a topical medication will help reduce sunlight induced redness and irritation in patients with rosacea.
CONDITIONS
Official Title
Evaluating Use of Topical Imipramine and Amitriptyline in Reducing Ultraviolet B Light-Induced Redness in Patients With Rosacea
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Fitzpatrick Skin Type I - IIII
- Self-identified rosacea or no history of flushing/blushing for controls
- Able to provide medical history and list of medications; control subjects must not take photosensitizing medications
You will not qualify if you...
- Using imipramine, amitriptyline or any other tricyclic antidepressant (oral or topical)
- Using topical anti-inflammatory agents within 1 week or systemic agents such as prednisone
- Large tattoos in the designated testing areas
- Tanning bed use within last 3 months
- Photodynamic Therapy or Ultraviolet B treatments in past 3 months
- Female subjects who are pregnant or nursing
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Wright State Physicians
Fairborn, Ohio, United States, 45324
Actively Recruiting
Research Team
M
Manager Clinical Research Operations
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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