Actively Recruiting
Evaluating the Usefulness of 18F-AlF-FAPI PET/CT Compared to 18F-FDG PET/CT for Diagnosis of Orbital Neoplasms
Led by Peking University Third Hospital · Updated on 2025-01-24
50
Participants Needed
1
Research Sites
232 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the usefulness of two imaging techniques, 18F-AlF-FAPI PET/CT and 18F-FDG PET/CT, for diagnosing and staging orbital tumors. The study focuses on comparing how well these scans detect primary and metastatic lesions in patients with suspected or newly diagnosed orbital neoplasms. The goal is to assess the accuracy of these imaging methods for better diagnosis. Participants undergo both 18F-AlF-FAPI PET/CT and 18F-FDG PET/CT scans around the same time as part of their initial evaluation. The amount of tumor detected is measured using the maximum standard uptake value (SUVmax). Researchers visually interpret the scans to count the number of metastatic lesions detected by each technique. They then calculate and compare sensitivity, specificity, and overall accuracy of both imaging methods. During the study, participants are monitored until the study completion, averaging about 6 months. Researchers collect and analyze data on diagnostic accuracy throughout this period. The study involves informed consent and follows ethical guidelines to protect participant rights and safety.
CONDITIONS
Official Title
Evaluating the Usefulness of 18F-AlF-FAPI PET/ CT in Orbital Neoplasms
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with suspected or newly diagnosed orbital neoplasms confirmed by MRI, CT, or pathology report
- Patients scheduled for both 18F-FDG and 18F-AlF-FAPI PET/CT scans
- Patients able to provide informed consent or assent according to clinical research ethics guidelines
You will not qualify if you...
- Pregnancy
- Breastfeeding
- Inability or unwillingness to provide written informed consent by the participant, parent, or legal representative
AI-Screening
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Trial Site Locations
Total: 1 location
1
Dept. of Nuclear Medicine, Peking University Third Hospital
Beijing, Beijing Municipality, China, 100191
Actively Recruiting
Research Team
H
Hui Li
L
Lingge Suo
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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