Actively Recruiting

Phase Not Applicable
Age: 3Years - 80Years
All Genders
ID06791226

Evaluating the Usefulness of 18F-AlF-FAPI PET/CT Compared to 18F-FDG PET/CT for Diagnosis of Orbital Neoplasms

Led by Peking University Third Hospital · Updated on 2025-01-24

50

Participants Needed

1

Research Sites

232 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the usefulness of two imaging techniques, 18F-AlF-FAPI PET/CT and 18F-FDG PET/CT, for diagnosing and staging orbital tumors. The study focuses on comparing how well these scans detect primary and metastatic lesions in patients with suspected or newly diagnosed orbital neoplasms. The goal is to assess the accuracy of these imaging methods for better diagnosis. Participants undergo both 18F-AlF-FAPI PET/CT and 18F-FDG PET/CT scans around the same time as part of their initial evaluation. The amount of tumor detected is measured using the maximum standard uptake value (SUVmax). Researchers visually interpret the scans to count the number of metastatic lesions detected by each technique. They then calculate and compare sensitivity, specificity, and overall accuracy of both imaging methods. During the study, participants are monitored until the study completion, averaging about 6 months. Researchers collect and analyze data on diagnostic accuracy throughout this period. The study involves informed consent and follows ethical guidelines to protect participant rights and safety.

CONDITIONS

Official Title

Evaluating the Usefulness of 18F-AlF-FAPI PET/ CT in Orbital Neoplasms

Who Can Participate

Age: 3Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with suspected or newly diagnosed orbital neoplasms confirmed by MRI, CT, or pathology report
  • Patients scheduled for both 18F-FDG and 18F-AlF-FAPI PET/CT scans
  • Patients able to provide informed consent or assent according to clinical research ethics guidelines
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Breastfeeding
  • Inability or unwillingness to provide written informed consent by the participant, parent, or legal representative

AI-Screening

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Trial Site Locations

Total: 1 location

1

Dept. of Nuclear Medicine, Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191

Actively Recruiting

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Research Team

H

Hui Li

L

Lingge Suo

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

Frequently Asked Questions

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