Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT06266403

Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

Led by Penn State University · Updated on 2025-01-13

300

Participants Needed

1

Research Sites

225 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers. The question is, What are the effects of communicative interaction on verbal communication in people with ALS? Participants will read words and sentences while they are in a solo setting and interactive setting.

CONDITIONS

Official Title

Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Speakers with amyotrophic lateral sclerosis (ALS) diagnosed by the revised EL Escorial criteria
  • No history of other neurological conditions like stroke
  • No cognitive impairment based on Telephone Montreal Cognitive Assessment (mini MoCA)
  • Detectable speech disturbance per ALS Functional Rating Scale-Revised (ALSFRS-R)
  • Ability to produce single words
  • Native speaker of American English
  • Age-matched adults passing remote hearing screening
  • No known speech, language, or neurological disorders by self-report
  • No cognitive impairment by Telephone Montreal Cognitive Assessment (mini MoCA)
  • Functionally native monolingual American English speakers
  • Unfamiliar interlocutors passing remote hearing screening
  • No known speech, language, or neurological disorders by self-report
  • Native monolingual American English speakers
  • No experience communicating with people with dysarthria
  • Aged between 18 and 40 years
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

Speech Core, Pennsylvania State University

University Park, Pennsylvania, United States, 16802

Actively Recruiting

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Research Team

A

Anne Olmstead, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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