Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05432024

Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging

Led by R&D Cardiologie · Updated on 2025-07-28

60

Participants Needed

1

Research Sites

264 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.

CONDITIONS

Official Title

Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients 18 years or older
  • Diagnosis of paroxysmal or persistent atrial fibrillation according to 2020 European Society of Cardiology Guidelines
  • Scheduled to undergo catheter ablation for cardiac arrhythmia using high power, short duration radiofrequency ablation, ultra-low temperature cryo ablation, or pulsed field ablation
Not Eligible

You will not qualify if you...

  • Known or suspected allergy to gadolinium
  • Contraindications to MRI such as claustrophobia, certain implants or devices, or high body mass index
  • Pregnancy or breastfeeding
  • Prior intervention in the left atrium, including ablation or surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

St. Antonius Hospital

Nieuwegein, Netherlands, 3435 CM

Actively Recruiting

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Research Team

L

Lucas VA Boersma, MD, PhD

CONTACT

B

Bob GS Abeln, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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