Surgery in esophageal and gastric cancer patients: what is the role for nutrition support in your daily practice?
Christophe Mariette, Marie-Laure De Botton, Guillaume Piessen
https://pubmed.ncbi.nlm.nih.gov/22322948Actively Recruiting
Led by University Hospital, Bordeaux · Updated on 2026-05-13
670
Participants Needed
1
Research Sites
N/A
Total Duration
U
University Hospital, Bordeaux
Lead Sponsor
F
French Eso-Gastric Tumors Working Group
Collaborating Sponsor
Malnutrition is commonly seen in patients diagnosed with esophageal or stomach cancers, affecting 65-80% of cases. It is linked to higher risks such as increased mortality, more postoperative complications, greater toxicity from chemoradiotherapy, and lower survival rates. Malnutrition may worsen during neoadjuvant treatment due to side effects like diarrhea and taste changes. There is currently no clear guidance on the type or duration of nutritional support during this treatment phase, and its impact on postoperative outcomes remains unclear. This observational study compares patients who receive enteral or parenteral nutrition through feeding jejunostomy during neoadjuvant treatment to those who do not receive such nutritional support. The goal is to evaluate how this perioperative nutritional support affects the rate of postoperative complications. Patients are grouped based on whether they received artificial nutrition during their treatment. The study focuses on assessing the presence and extent of postoperative complications within 30 days after surgery. Participants will undergo surgery for esophageal cancer while being monitored for their nutritional status before and during treatment. Researchers will track postoperative complications using the Clavien classification system at 30 days post-surgery. The study involves observing outcomes related to nutrition and surgical recovery without altering standard care. Participants' health status and treatment responses will be evaluated throughout the study period to better understand how nutritional support influences surgical outcomes.
CONDITIONS
Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Duration of neoadjuvant treatment
Participants who undergo routine care are observed during neoadjuvant treatment, with or without enteral or parenteral nutrition.
Visits as part of routine clinical care
Duration - Up to 30 days post-surgery
Participants undergo surgery for esophageal or stomach cancer followed by immediate post-operative care.
Approximately 1 to 2 visits during hospitalization and early recovery
Total: 1 location
1
Hopîtal du Haut Lévêque
Pessac, France, 33600
Actively Recruiting
C
Caroline GRONNIER, PhD, MD
V
Valérie AURILLAC
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Have more questions? Get in touch with our team for quick support
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Christophe Mariette, Marie-Laure De Botton, Guillaume Piessen
https://pubmed.ncbi.nlm.nih.gov/22322948Irene Deftereos, Nicole Kiss, Elizabeth Isenring...
https://pubmed.ncbi.nlm.nih.gov/32336624Irene Deftereos, Justin M-C Yeung, Janan Arslan...
https://pubmed.ncbi.nlm.nih.gov/34579082