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ID07584577

Study on the Effect of Feeding Tube Nutrition During Pre-Surgery Treatment on Complications After Surgery for Esophageal or Stomach Cancer

Led by University Hospital, Bordeaux · Updated on 2026-05-13

670

Participants Needed

1

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Malnutrition is commonly seen in patients diagnosed with esophageal or stomach cancers, affecting 65-80% of cases. It is linked to higher risks such as increased mortality, more postoperative complications, greater toxicity from chemoradiotherapy, and lower survival rates. Malnutrition may worsen during neoadjuvant treatment due to side effects like diarrhea and taste changes. There is currently no clear guidance on the type or duration of nutritional support during this treatment phase, and its impact on postoperative outcomes remains unclear. This observational study compares patients who receive enteral or parenteral nutrition through feeding jejunostomy during neoadjuvant treatment to those who do not receive such nutritional support. The goal is to evaluate how this perioperative nutritional support affects the rate of postoperative complications. Patients are grouped based on whether they received artificial nutrition during their treatment. The study focuses on assessing the presence and extent of postoperative complications within 30 days after surgery. Participants will undergo surgery for esophageal cancer while being monitored for their nutritional status before and during treatment. Researchers will track postoperative complications using the Clavien classification system at 30 days post-surgery. The study involves observing outcomes related to nutrition and surgical recovery without altering standard care. Participants health status and treatment responses will be evaluated throughout the study period to better understand how nutritional support influences surgical outcomes.

CONDITIONS

Brief Title

Evaluation of the Administration of Artificial Nutrition by Feeding Jejunostomy During Neoadjuvant Treatment on Postoperative Morbidity in the Context of Esophageal or Stomach Cancer

Research Team

C

Caroline GRONNIER, PhD, MD

V

Valérie AURILLAC

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