Actively Recruiting
Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer
Led by University Hospital, Grenoble · Updated on 2024-05-20
23
Participants Needed
1
Research Sites
142 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Ovarian cancer is associated with undernutrition in more than half of all cases. The current management of undernutrition-cachexia in cancer is not specific. It is well recognized that the nutritional support currently offered to cancer patients is not effective in combating cachexia, which progresses inexorably, leading to the patient's death. It is therefore necessary to offer specific and adapted care, in particular by optimizing the quality of nitrogen intake. To achieve this, the investigators first need to define the specific amino acid requirements of cancer patients.
CONDITIONS
Official Title
Evaluation of Amino Acid Metabolism Changes in Ovarian Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histological diagnosis of high-grade serous ovarian cancer not immediately resectable (stage III or IVa) managed at Grenoble Alpes University Hospital
- Affiliation to the French social security system
- Able to understand and follow the instructions necessary for the conduct of the trial
- Provided written consent for the study
You will not qualify if you...
- Significant active comorbidity requiring long-term drug treatment (e.g. organ failure, diabetes) or history of conditions affecting amino acid metabolism (e.g. urea or homocysteine cycle abnormalities, tyrosinemia, alkaptonuria, hyperprolinemia, organic aciduria)
- Vegetarian or vegan diet
- Difficult venous access
- Protected persons such as pregnant women, nursing mothers, persons deprived of liberty, or those under legal protection
- Received over 4,500 euros compensation for other human research participation in the past 12 months
- Significant unexplained biological abnormalities
- Presence of liver metastases
AI-Screening
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Trial Site Locations
Total: 1 location
1
CHU Grenoble Alpes
La Tronche, France
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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