Study of Knee Ligament Laxity in Healthy Women Aged 18 to 40 With and Without Hormone Therapy

What this Trial Is About

Women have a higher risk of anterior cruciate ligament ACL injury compared to men, with several factors such as ligament looseness and hormonal changes during menstrual cycles potentially influencing this risk. Researchers are studying how hormone therapy, particularly the effects of estrogen and progestin contraception, might affect knee ligament laxity in healthy women. This study aims to better understand the relationship between hormonal impregnation and ligament looseness, which has not been previously explored in detail. Participants will be divided into three groups based on their hormonal contraception use women using estrogen-progestin contraception, women using progestin-only contraception, and women not using hormonal contraception. Each group follows specific contraceptive protocols or has regular menstrual cycles. The study involves tests like the Beighton test for hypermobility and the Lachman test to measure knee ligament looseness. Questionnaires about contraception use and sports activities are also part of the study. Women aged 18 to 40 can participate and will be assessed at specific points in their menstrual cycle or contraception use. Researchers will measure changes in anterior tibial knee translation over 24 months, along with factors like height, weight, age, contraceptive duration, and cycle length. Safety and eligibility are monitored through criteria such as pregnancy status, medical history, and lifestyle factors. The study includes informed consent and social security affiliation requirements to ensure participant safety and compliance.

Evaluation of Anterior Tibial Knee Translation in Healthy Women With and Without Hormone Therapy