Comparing Autogenous Demineralized Dentin Graft and Autogenous Bone Graft for Treating Periodontal Intrabony Defects Using a Modified Minimally Invasive Surgery

What this Trial Is About

Researchers are evaluating the use of autogenous demineralized dentin as a bone graft substitute compared to autogenous bone graft in treating periodontal intrabony defects in patients with periodontitis. The study aims to develop a newer, less invasive, and cost-effective treatment approach using the participants own extracted teeth. The main question is whether this dentin graft can achieve similar clinical attachment gain and bone fill as traditional bone grafts following a modified minimally invasive surgical technique M-MIST. Participants will be divided into two groups. The intervention group receives a graft made from their freshly extracted teeth that are cleaned, ground, and demineralized before placement in the defect. The control group receives an autogenous bone graft harvested from the retromolar area. Both groups undergo the M-MIST surgical technique, which involves limited flap elevation and precise suturing. Initial therapy includes oral hygiene instructions and cleaning, followed by surgical intervention after 4-6 weeks. Follow-up visits occur at 1, 3, and 6 months. Participants will be evaluated through clinical and radiographic assessments including clinical attachment level gain, linear bone fill, gingival and plaque indices, probing pocket depth, gingival recession, bleeding on probing, postoperative pain, and patient satisfaction. Measurements are taken at baseline and at multiple points during the 6-month follow-up. Postoperative care includes medication, mouthwash, and instructions for oral hygiene. The study lasts for six months, with evaluations performed by a single calibrated examiner to ensure consistency.

Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects