Actively Recruiting
Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral Neuromodulation
Led by University Hospital, Lille · Updated on 2026-05-06
40
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Overactive bladder syndrome (OAB) is defined by urgent and frequent urges to urinate associated with frequent night-time urination and sometimes urinary incontinence. Sacral neuromodulation (SNM) is now one of the second-line treatments for OAB. The mode of action of SNM is still poorly understood but a number of data from recent scientific literature suggest that SNM may act, among other things, by altering the balance of the autonomic nervous system (ANS) - located at the interface between the urinary tract and the brain structures regulating the functioning of the urinary tract. The aim of this study would therefore be to develop a predictive tool for the effectiveness of SNM.
CONDITIONS
Official Title
Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral Neuromodulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female aged 18 years or older
- Diagnosed with overactive bladder syndrome
- Indicated for a two-staged sacral neuromodulation procedure
- Undergoing general anesthesia with Remifentanil and Propofol
- Provided written consent to participate
- Willing to comply with all study procedures and duration
You will not qualify if you...
- Received tibial neuro-stimulation in the last 3 months
- Received sacral neuromodulation in the last 3 months
- Received botulinum toxin A intra-detrusor injection in the last 9 months
- Currently pregnant
- Administrative reasons preventing participation
- Under guardianship or curatorship
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
chu de Lille
Lille, France
Actively Recruiting
Research Team
D
DRI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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