Actively Recruiting

Age: 21Years - 80Years
FEMALE
Healthy Volunteers
NCT04014829

Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy

Led by KK Women's and Children's Hospital · Updated on 2024-11-26

436

Participants Needed

1

Research Sites

436 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Phase 1 (started in July 2019): Central Sensitization Inventory (CSI), Fear-Avoidance Components Scale (FACS), pain-pressure threshold are factors associated with chronic post-hysterectomy pain (CPHP), but a complete understanding on the development of CPHP is lacking. The study aims to identify clinically-relevant factors for CPHP that can be reliably assessed preoperatively. === Phase 2 (anticipated start May 2022): In addition to above factors, the association between heart rate variability (HRV) parameters, anxiety level, anticipated pain, and anticipated analgesia requirement with significant postoperative pain and CPHP will be investigated.

CONDITIONS

Official Title

Evaluation of Central Sensitization, Fear-Avoidance, and Pain-Pressure Threshold With Chronic Pain After Hysterectomy

Who Can Participate

Age: 21Years - 80Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 21 to 80 years old
  • American Society of Anesthesiologists Physical Scale (ASA) I to III
  • Benign gynaecological indications for hysterectomy
  • Elective abdominal or laparoscopic hysterectomy
Not Eligible

You will not qualify if you...

  • Vaginal hysterectomy
  • Uterine prolapse, endometriosis, malignant disease, or pelvic pain as main indication for surgery
  • History of drug dependence or recreational drug use
  • History of chronic pain syndrome
  • Current chronic daily treatment with corticosteroids, excluding inhaled steroids
  • Allergy to study drugs
  • Major heart surgery
  • Heart transplant
  • Pacemaker inserted
  • Baseline non-sinus cardiac rhythm

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

KK Women's and Children's Hospital

Singapore, Singapore, 229899

Actively Recruiting

Loading map...

Research Team

B

Ban Leong Sng, MBBS

CONTACT

H

Hon Sen Tan, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here