Actively Recruiting
Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted to Intensive Care for Septic Shock.
Led by Centre Hospitalier de Lens · Updated on 2026-05-08
200
Participants Needed
5
Research Sites
166 weeks
Total Duration
On this page
Sponsors
C
Centre Hospitalier de Lens
Lead Sponsor
U
University Hospital, Lille
Collaborating Sponsor
AI-Summary
What this Trial Is About
The aim of the study is to demonstrate that "frail" patients, defined as having a CFS score greater than or equal to 5, and "severely" frail patients, defined as having a CFS score between \[6-7\] as defined by Bagshaw et al (14), constitute an independent risk factor (RF) for mortality. In the same way, as an exploratory study, we will try to find out whether clinical frailty constitutes a risk factor for extending the length of hospital stay, the risk of short/medium-term readmission, as has already been demonstrated for patients admitted to intensive care from all causes (15), or for impaired quality of life. The objective is to have a better understanding of the implications and outcomes associated with pre-hospital frailty in young critically ill patients. This analysis will also help to clarify prognoses and contribute to better decision-making on the intensity and proportionality of care, as well as providing better information and helping to manage the expectations of patients and their families in terms of survival prognosis and subsequent quality of life.
CONDITIONS
Official Title
Evaluation of the Clinical Frailty Scale (CFS) as a Risk Factor of Mortality in Adult Patients ≤65 Years of Age Admitted to Intensive Care for Septic Shock.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years and up to 65 years
- Patient admitted to intensive care - resuscitation
- Patient admitted for suspected or documented type 3 sepsis
- Presence of vasopressor amines to maintain MAP > 65mmHg despite filling
- Lactatemia 2 mmol/L or higher on admission
You will not qualify if you...
- Patient moribund on admission
- Severe pre-existing dementia or cognitive decline preventing independent living, including severe neurodegenerative diseases and mental illness requiring institutionalization
- Pregnant women or women in labor
- Patients under guardianship or curatorship
- Patients deprived of their liberty
- Patient and/or family unable to speak or understand French
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
Ch Germon Et Gauthier
Béthune, France, 62408
Actively Recruiting
2
CH Boulogne sur Mer
Boulogne-sur-Mer, France, 62321
Actively Recruiting
3
CHU de Dijon
Dijon, France, 21079
Actively Recruiting
4
CH de Lens
Lens, France
Actively Recruiting
5
CHU Lille
Lille, France, 59037
Actively Recruiting
Research Team
G
Guillaume DEGOUY, Dr
CONTACT
M
MELANIE VERLAY
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here