Actively Recruiting
Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint
Led by Istituto Ortopedico Rizzoli · Updated on 2026-01-30
100
Participants Needed
1
Research Sites
192 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Various techniques for the fixation of unstable osteochondral fragments have been used over the years, each with associated advantages and disadvantages, and differing clinical outcomes. However, the literature on the treatment of this type of injury in the adolescent and young adult population is scarce and involves small case series. Failure to treat these injuries can lead to serious consequences such as chronic pain, residual joint stiffness, and the development of early osteoarthritis, necessitating more invasive and burdensome interventions for the national health system, such as prosthetic replacements or osteotomies. Due to the lack of real consensus within the scientific community regarding the ideal treatment for these patients and the insufficient medium/long-term follow-up data on the effects of these injuries on articular cartilage in young patients, this study aims to evaluate the clinical and radiological conditions of patients undergoing osteochondral fragment fixation using the same surgical technique (fixation with resorbable screws performed arthroscopically or via open surgery depending on the lesion's location) in order to clarify preventive measures against cartilage degeneration following these injuries, which are very common in adolescence.
CONDITIONS
Official Title
Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing surgical fixation of osteochondral fragments using resorbable screws, either arthroscopically or via mini-open procedure, from 01/01/2017 and new patients eligible until 31/12/2025
- Patients aged between 12 and 35 years at surgery
- Presence of osteochondral fragments confirmed by magnetic resonance imaging
- Osteochondral lesions seen on imaging with symptoms caused by these fragments
- Patients diagnosed with osteochondritis dissecans or recent contusion/sprain trauma
You will not qualify if you...
- Patients with complex ligament injuries or fractures at the time of surgery
- Patients who cannot be reached for follow-up
- Women of childbearing age who cannot exclude pregnancy
- Patients unable or unwilling to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS Rizzoli Orthopedic Institute
Bologna, Bologna, Italy, 40136
Actively Recruiting
Research Team
S
Stefano Zaffagnini
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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