Actively Recruiting

Age: 12Years - 35Years
All Genders
NCT06462040

Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint

Led by Istituto Ortopedico Rizzoli · Updated on 2026-01-30

100

Participants Needed

1

Research Sites

192 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Various techniques for the fixation of unstable osteochondral fragments have been used over the years, each with associated advantages and disadvantages, and differing clinical outcomes. However, the literature on the treatment of this type of injury in the adolescent and young adult population is scarce and involves small case series. Failure to treat these injuries can lead to serious consequences such as chronic pain, residual joint stiffness, and the development of early osteoarthritis, necessitating more invasive and burdensome interventions for the national health system, such as prosthetic replacements or osteotomies. Due to the lack of real consensus within the scientific community regarding the ideal treatment for these patients and the insufficient medium/long-term follow-up data on the effects of these injuries on articular cartilage in young patients, this study aims to evaluate the clinical and radiological conditions of patients undergoing osteochondral fragment fixation using the same surgical technique (fixation with resorbable screws performed arthroscopically or via open surgery depending on the lesion's location) in order to clarify preventive measures against cartilage degeneration following these injuries, which are very common in adolescence.

CONDITIONS

Official Title

Evaluation of Clinical and Radiological Outcomes in Patients Undergoing Fixation of Osteochondral Fragments With Reasorbable Screws in the Knee Joint

Who Can Participate

Age: 12Years - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing surgical fixation of osteochondral fragments using resorbable screws, either arthroscopically or via mini-open procedure, from 01/01/2017 and new patients eligible until 31/12/2025
  • Patients aged between 12 and 35 years at surgery
  • Presence of osteochondral fragments confirmed by magnetic resonance imaging
  • Osteochondral lesions seen on imaging with symptoms caused by these fragments
  • Patients diagnosed with osteochondritis dissecans or recent contusion/sprain trauma
Not Eligible

You will not qualify if you...

  • Patients with complex ligament injuries or fractures at the time of surgery
  • Patients who cannot be reached for follow-up
  • Women of childbearing age who cannot exclude pregnancy
  • Patients unable or unwilling to provide informed consent

AI-Screening

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Trial Site Locations

Total: 1 location

1

IRCCS Rizzoli Orthopedic Institute

Bologna, Bologna, Italy, 40136

Actively Recruiting

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Research Team

S

Stefano Zaffagnini

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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