Actively Recruiting

Age: 0 - 18Years
All Genders
ID06776133

Evaluation of the Correlation Between Inferior Vena Cava Size and Right Atrial Pressure in Children and Development of a Predictive Model

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-15

1100

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating the relationship between ultrasound measurements of the inferior vena cava (IVC) and right atrial pressure (RAP) in children and adolescents up to 18 years old. The study aims to create a mathematical model that can predict RAP in pediatric patients using echocardiographic data. This observational study is conducted at a single center and includes both retrospective and prospective data collection. The study involves analyzing ultrasound measurements of the IVC, including maximum and minimum diameters expressed as z-scores and ratios involving the aorta's systolic diameter. Researchers will use these data along with patient growth measurements to develop a pediatric-specific predictive model of RAP. Additionally, they will test the accuracy of an existing adult RAP estimation model in the pediatric population. Participants will be pediatric patients who have central venous catheters placed as part of their diagnosis at the study center. The study includes collecting ultrasound and clinical data retrospectively and prospectively. The main outcome is the development of a predictive mathematical model of RAP based on echocardiographic parameters. The study focuses on conditions including congenital and acquired heart disease, and participation involves consent from the parent or guardian for minors.

CONDITIONS

Official Title

Evaluation of the Correlation Between Vein Size Inferior Cava and Right Atrial Pressure in Pediatric Age and Creation of a Possible Predictive Model

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric patients aged 0-18 years undergoing central venous catheter (CVC) placement at the study center
  • Obtaining informed consent from parent or guardian for minors
Not Eligible

You will not qualify if you...

  • Patients with univentricular cardiac physiology
  • Patients with nonsinus heart rhythm
  • Patients on mechanical ventilation
  • Patients with inferior vena cava thrombosis
  • Patients with isomerism

AI-Screening

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Trial Site Locations

Total: 1 location

1

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Bologna, Italy, 40138

Actively Recruiting

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Research Team

S

Simone Bonetti, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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