Actively Recruiting

All Genders
Healthy Volunteers
NCT05774093

Evaluation of COVID-19 Immune Barrier and Reinfection Risk

Led by Sun Yat-sen University · Updated on 2023-03-17

300

Participants Needed

1

Research Sites

229 weeks

Total Duration

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AI-Summary

What this Trial Is About

The goal of this observational study is to evaluate the protective effect of immune barrier on secondary infection after COVID-19 (coronavirus disease 2019) vaccination or COVID-19 virus Omicron B A. 5.2 strain infection by dynamically monitoring the COVID-19 antibody titer, cellular immune function and the occurrence of secondary infection of healthy participants, mainly medical staff in our hospital, to understand the cross protective effect of COVID-19 antibody on different variants of Omicron, and explore the best time to use COVID-19 vaccine to strengthen immunity after Omicron mutant infection.

CONDITIONS

Official Title

Evaluation of COVID-19 Immune Barrier and Reinfection Risk

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • No age or gender restrictions
  • Medical, nursing, administrative, or logistics staff at the Third Affiliated Hospital of Sun Yat-Sen University or other participants able to cooperate with 48 weeks of follow-up
  • Must know whether they have been infected with COVID-19 and remember the date of first infection if applicable
Not Eligible

You will not qualify if you...

  • Serious respiratory diseases such as asthma, bronchiectasis, chronic obstructive pulmonary disease, pulmonary interstitial disease, tuberculosis, or other respiratory conditions that may interfere with symptom observation
  • Serious diseases or histories affecting immune function, including uncontrolled or unresectable cancers, blood diseases, cachexia, active bleeding, severe malnutrition, mental illnesses, autoimmune diseases, HIV, and similar conditions
  • Plans for long-term assignments that prevent regular hospital follow-up

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Third Affiliated Hospital of Sun Yat-sen University

Guangzhou, Guangdong, China, 510630

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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