Study of Ru-Yi-Jin-Huang-Saan Patch for Treating Colles Fracture After Surgery Randomized, Double-blind, Placebo-Controlled Phase 2 Trial

What this Trial Is About

This research aims to evaluate the safety and effectiveness of Ru-Yi-Jin-Huang-Saan for treating Colles fracture. The study focuses on adults aged 20 to 80 who have undergone surgical fixation for this wrist fracture. Given the aging population and increased fracture risks, traditional Chinese medicine is being studied for its potential role in aiding bone healing and reducing complications. Participants are randomly assigned to receive either the Ru-Yi-Jin-Huang-Saan patch or a placebo patch containing starch. Both patches are applied topically twice daily for six days. This randomized, double-blind trial compares these two groups to assess the effect of the herbal treatment on wrist recovery. During the study, participants will have their wrist function and pain evaluated using the Patient-Rated Wrist Evaluation PRWE scale at the start and on day six. Additional assessments include blood tests measuring C-reactive protein and ultrasound imaging to monitor healing progress. The trial is designed to carefully monitor safety and treatment effects over the six-day period, providing detailed insights into the herbal patchs impact on fracture recovery.

Evaluation of the Curative Effect of Ru-Yi-Jin-Huang-Saan