Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06913738

Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder

Led by AddiPsy · Updated on 2025-04-09

154

Participants Needed

2

Research Sites

284 weeks

Total Duration

On this page

Sponsors

A

AddiPsy

Lead Sponsor

C

Clinique Caradoc

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate whether a dimensional adaptation of Good Psychiatric Management (called GPM-extended) is more effective than classic Good Psychiatric Management (GPM) in treating adult patients with borderline personality disorder (BPD). Briefly, the GPM-extended model integrates elements from existing adaptations of GPM for narcissistic and obsessive-compulsive personality disorders. It aims to provide a more personalized and dimensional approach to treatment, tailored to each patient's specific personality dysfunction and interpersonal triggers. The main questions it aims to answer are: * Does GPM-extended improve overall BPD symptom severity more than classic GPM after one year of treatment? * Does GPM-extended lead to better outcomes in related clinical domains (e.g., personality functioning, emotional regulation, social functioning...) ? Researchers will compare two groups: * Patients treated in a center using the GPM-extended program. * Patients treated in a center using the classic GPM program. In each group, patients will receive weekly outpatient psychiatric care for one year. In terms of evaluation, patients will be evaluated at baseline, 4 months, 8 months, and 1 year. They will undergo both clinician-administered and self-report assessments to measure BPD symptoms and other relevant psychological dimensions. This study hopes to contribute to the development of dimensional evidence-based treatments for personality disorders.

CONDITIONS

Official Title

Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults (≥18 years old)
  • Diagnosed with borderline personality disorder by meeting at least 5 out of 9 SCID-II criteria
  • Provided written informed consent
  • Affiliated with or beneficiary of the French national health insurance system
Not Eligible

You will not qualify if you...

  • Younger than 18 years old
  • Having a comorbid psychotic disorder, intellectual disability, severe antisocial traits, major substance use disorder incompatible with intensive therapy without abstinence, anorexia nervosa with somatic risk, or bipolar disorder in acute manic phase
  • Under legal protection such as guardianship or legal safeguard
  • Unable to cooperate or complete self- or clinician-administered questionnaires
  • Not affiliated with or not beneficiary of the French national health insurance system

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 2 locations

1

Clinique Caradoc

Bayonne, France, 64100

Actively Recruiting

2

Addipsy

Lyon, France, 69007

Actively Recruiting

Loading map...

Research Team

M

Martin Blay, M.D., M.Sc

CONTACT

F

Frédéric Mazenod

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here