Actively Recruiting
Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder
Led by AddiPsy · Updated on 2025-04-09
154
Participants Needed
2
Research Sites
284 weeks
Total Duration
On this page
Sponsors
A
AddiPsy
Lead Sponsor
C
Clinique Caradoc
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate whether a dimensional adaptation of Good Psychiatric Management (called GPM-extended) is more effective than classic Good Psychiatric Management (GPM) in treating adult patients with borderline personality disorder (BPD). Briefly, the GPM-extended model integrates elements from existing adaptations of GPM for narcissistic and obsessive-compulsive personality disorders. It aims to provide a more personalized and dimensional approach to treatment, tailored to each patient's specific personality dysfunction and interpersonal triggers. The main questions it aims to answer are: * Does GPM-extended improve overall BPD symptom severity more than classic GPM after one year of treatment? * Does GPM-extended lead to better outcomes in related clinical domains (e.g., personality functioning, emotional regulation, social functioning...) ? Researchers will compare two groups: * Patients treated in a center using the GPM-extended program. * Patients treated in a center using the classic GPM program. In each group, patients will receive weekly outpatient psychiatric care for one year. In terms of evaluation, patients will be evaluated at baseline, 4 months, 8 months, and 1 year. They will undergo both clinician-administered and self-report assessments to measure BPD symptoms and other relevant psychological dimensions. This study hopes to contribute to the development of dimensional evidence-based treatments for personality disorders.
CONDITIONS
Official Title
Evaluation of a Dimensional Adaptation of Good Psychiatric Management (GPM-extended) for the Treatment of Borderline Personality Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults (≥18 years old)
- Diagnosed with borderline personality disorder by meeting at least 5 out of 9 SCID-II criteria
- Provided written informed consent
- Affiliated with or beneficiary of the French national health insurance system
You will not qualify if you...
- Younger than 18 years old
- Having a comorbid psychotic disorder, intellectual disability, severe antisocial traits, major substance use disorder incompatible with intensive therapy without abstinence, anorexia nervosa with somatic risk, or bipolar disorder in acute manic phase
- Under legal protection such as guardianship or legal safeguard
- Unable to cooperate or complete self- or clinician-administered questionnaires
- Not affiliated with or not beneficiary of the French national health insurance system
AI-Screening
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Trial Site Locations
Total: 2 locations
1
Clinique Caradoc
Bayonne, France, 64100
Actively Recruiting
2
Addipsy
Lyon, France, 69007
Actively Recruiting
Research Team
M
Martin Blay, M.D., M.Sc
CONTACT
F
Frédéric Mazenod
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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