Actively Recruiting

Phase Not Applicable
Age: 18Years - 69Years
All Genders
Healthy Volunteers
ID07443215

Evaluation of Effect of Scatter on Visual Performance

Led by Johnson & Johnson Vision Care, Inc. · Updated on 2026-05-08

36

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate how different levels of optical scatter affect visual performance in adults aged 18 to 69 years. It recognizes that eye scatter changes with age and may impact younger and older adults differently, focusing on visual acuity as a key measure. The study is a randomized, single-masked, crossover trial conducted at a single site, comparing the effects of various filter sizes on vision. Participants will be assigned randomly to different sequences involving no filter or one of five filter sizes (1/4mm, 1/2mm, 1mm, 2mm) while wearing either ACUVUEOASYS 1-Day Sphere lenses for non-presbyopic participants or ACUVUEOASYS Multifocal lenses for presbyopic participants. Each participant will experience all filter conditions in a crossover design over three visits without dispensing the filters. During the study, participants will have their distance monocular high luminance high contrast visual acuity measured after lens fitting. Researchers will assess visual performance under each scatter condition. The trial involves three visits at the study site and includes monitoring for visual acuity changes under different scattering conditions. The total duration of participation is defined by the three visits required for the crossover evaluations.

CONDITIONS

Brief Title

Evaluation of Effect of Scatter on Visual Performance

Who Can Participate

Age: 18Years - 69Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 18 and 69 years of age (inclusive) at the time of screening.
  • Habitually wear soft contact lenses (spherical or multifocal) in both eyes for at least 6 hours per day, at least 2 days per week over the past 30 days.
  • Ability and willingness to follow study instructions.
  • Possess a wearable pair of glasses that correct distance vision.
  • Have a spherical distance prescription between +3.00 and -5.00 diopters in both eyes.
  • Have a cylindrical component less than 1.00 diopter in both eyes.
  • Best corrected monocular distance visual acuity of 20/25 or better in each eye.
  • Have near addition with add refinement less than 0.75D for non-presbyopes or 0.75D or greater for presbyopes.
Not Eligible

You will not qualify if you...

  • Currently pregnant or lactating.
  • Diabetic.
  • Currently using ocular medications or have any ocular infection.
  • Have ocular or systemic allergies, diseases, infections, or medications that interfere with contact lens wear or study results, including serious infectious or immunosuppressive diseases.
  • Have worn rigid gas permeable, orthokeratology, or hybrid lenses in the past 6 months.
  • Currently wearing lenses in extended wear modality.
  • History of strabismus or amblyopia.
  • Employed at the study site or immediate family member of such an employee.
  • Participated in a contact lens or lens care clinical trial within 7 days prior to enrollment.
  • Have clinically significant ocular abnormalities or diseases that contraindicate contact lens wear.
  • Have vision fluctuations due to dry eye or other ocular conditions.
  • Have had or planned ocular surgery during the study period (e.g., LASIK).

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Short-term exposures during the trial period

Participants are fitted with different contact lens filters in a randomized sequence to evaluate their effect on visual performance.

Multiple visits to try each lens filter as per randomized sequence

Trial Site Locations

Total: 1 location

1

VRC

Jacksonville, Florida, United States, 32256

Actively Recruiting

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Research Team

S

Study Contact

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

5

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