Actively Recruiting

Phase 3
Age: 18Years - 40Years
All Genders
NCT05681312

Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars

Led by University of Baghdad · Updated on 2024-05-08

55

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

1. To compare the postoperative pain between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 2. To compare the postoperative swelling (edema) between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 3. To compare the degree of trismus between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day. 4. Measure patients' perceptions of changes in their quality of life in the postoperative period and compare it between the patients who receive the systemic enzyme therapy and patients in the control group in the third and seventh day.

CONDITIONS

Official Title

Evaluation of the Effect of Systemic Proteolytic Enzyme Therapy on Postoperative Inflammatory Response and QoL After Surgical Extraction of Impacted Mandibular Third Molars

Who Can Participate

Age: 18Years - 40Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy patients over 18 years old of either gender
  • Patients who have impacted mandibular third molar
  • Ability to tolerate surgical procedure
  • Pell and Gregory's classification (Class I and class II, position A and B)
Not Eligible

You will not qualify if you...

  • Patients with uncontrolled systemic diseases
  • Patients with history of chemotherapy or radiotherapy therapy to the head and neck region
  • Acute infection at the surgical site at time of operation
  • The presence of cysts or tumors associated with the impacted teeth
  • Pell and Gregory's classification (class III Position C)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Dunya Abdulmuniem Mahmood

Baghdad, Iraq, 10011

Actively Recruiting

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Research Team

D

Dunya Abdulmuniem

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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