Actively Recruiting
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
Led by Harran University · Updated on 2025-09-18
54
Participants Needed
1
Research Sites
37 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars. Additionally, the effects on periodontal health will be examined by comparing the gum healing processes of patients using both mouthwashes.The main questions it aims to answer are: 1. Tea tree oil, said to have anti-inflammatory and antibacterial effects, could be an alternative to chlorhexidine in reducing postoperative complications after impacted tooth extraction. 2. Does tea tree oil, which has antimicrobial effects, have as positive an impact on periodontal health as chlorhexidine?Researchers will compare tea tree oil to chlorhexidine (routinely prescribed after the extraction of an impacted wisdom tooth) to see if tea tree oil works to decrease postoperative complications. Participants will: For 7 days after the operation, they will gargle with chlorhexidine mouthwash or mouthwash containing tea tree oil 3 times a day. They will come to the clinic for check-ups and measurements on the 2nd and 7th days after the operation. They will record their pain levels and the number of painkillers they take daily.
CONDITIONS
Official Title
Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals undergoing extraction of Class 2, Class B mandibular third molars impacted in the lower jaw
- Aged between 18 and 65 years
- In stable general health without serious cardiovascular or kidney disease
- Willing to use tea tree extract or other treatments
You will not qualify if you...
- Known allergy or hypersensitivity to tea tree extract
- Serious illnesses such as heart failure, kidney disease, or bleeding disorders
- Pregnancy or breastfeeding
- Taking medications that may interact with tea tree extract like blood thinners or antihypertensives
- Previously treated for edema
- Chronic edema
AI-Screening
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Trial Site Locations
Total: 1 location
1
Harran University, Faculty of Dentistry
Sanliurfa, Turkey (Türkiye)
Actively Recruiting
Research Team
M
Mine alkaya karagoz
CONTACT
F
fatih yenigun
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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