Actively Recruiting
Evaluation of an Educational Intervention on Infectious Risk Knowledge and Vaccination Experience in Patients Without a Functioning Spleen at an Intra-hospital Outpatient Clinic
Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2026-02-02
100
Participants Needed
2
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying patients who have had their spleen removed or have a non-functioning spleen, a condition known as asplenia, which increases the risk of serious infections like overwhelming post-splenectomy infection (OPSI). This research evaluates how an educational intervention improves patient knowledge and awareness of infection risks and preventive measures. The study is observational and conducted at a single academic hospital, focusing on vaccination and infection prevention in these patients. The study involves an educational intervention delivered by the hospital's vaccination team during inpatient consultations. Patients receive information about asplenia-related infection risks and preventive steps, including vaccination schedules for diseases such as pneumococcus, meningococcus, and influenza. Educational materials like brochures and vaccination schedules support this intervention. Patient knowledge and attitudes are assessed before and after the intervention using questionnaires. Those completing the vaccination process also share their experience with vaccination management. Participants are followed over time through outpatient visits or phone interviews to monitor vaccination uptake, schedule completion, and ongoing care after discharge. Clinical, demographic, and vaccination data are collected and stored securely following privacy standards. The main outcome measured is the change in knowledge and risk perception about infections over 24 months. Secondary outcomes include patient experience with vaccination, links between knowledge and demographics, and adherence to the vaccination pathway.
CONDITIONS
Brief Title
Evaluation of the Effectiveness of an Educational Intervention in Splenectomized Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients (18 years old or older)
- Patients splenectomized at Fondazione Policlinico Universitario A. Gemelli IRCCS
- Patients who have a vaccination consultation requested during hospitalization
- Patients who provide signed informed consent for study participation and data use
You will not qualify if you...
- Minor patients
- Patients without signed informed consent for participation and data processing
- Patients splenectomized at other healthcare facilities
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 24 months
Participants receive an educational intervention about asplenia, infectious risks, and vaccination prophylaxis, supported by informational materials, and attend vaccination consultations as part of routine care.
Outpatient visits and structured telephone interviews as needed
Duration - Up to 24 months
Participants are followed longitudinally to monitor education impact, vaccination uptake, adherence to recommended schedules, and continuity of care through outpatient visits or telephone interviews.
Outpatient visits and structured telephone interviews as needed
Trial Site Locations
Total: 2 locations
1
Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome, Lazio, Italy, 00168
Actively Recruiting
2
Fondazione Policlinico Universitario A. Gemelli IRCCS
Roma, Italy, 00168
Actively Recruiting
Research Team
L
LAURENTI PATRIZIA, PROFESSOR
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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