Study Comparing Safety and Effectiveness of Two Approaches for Treating Chronic Total Occlusions in Coronary Arteries Observational Research on Long-Term Outcomes and Factors Influencing Treatment Methods

What this Trial Is About

Researchers are studying patients with chronic total occlusion CTO of the coronary artery to compare two different procedural approaches the antegrade and retrograde methods. The study aims to analyze clinical, anatomical, and procedural differences between patients who underwent each approach, evaluate the success rates and complication patterns, and assess long-term outcomes after successful procedures. It also seeks to identify factors that influence the need for the retrograde approach and prognostic factors related to long-term results. Participants are those who have at least one CTO lesion in an epicardial coronary artery with a diameter of 2.5 mm or more and exhibit symptoms of angina or confirmed myocardial ischemia. The study observes patients who underwent either the antegrade or retrograde percutaneous coronary intervention PCI approach. It is an observational study without experimental interventions, focusing on detailed clinical and procedural data collection. The study follows patients for long-term outcomes, with primary measures assessed at 12 months post-PCI and secondary measures annually up to five years. During the study, participant data including procedure success, occurrence of death, myocardial infarction, and target vessel revascularization or reocclusion are tracked. Safety and effectiveness outcomes are evaluated through clinical follow-ups and medical records review. The studys total duration extends up to five years to monitor long-term performance and complications after PCI. Participants provide informed consent and agree to follow-up plans approved by institutional review boards.

Evaluation of Effectiveness and Safety of Antegrade and Retrograde Approach of Percutaneous Coronary Intervention for Chronic Total Occlusions