Evaluation of the Effects of Ketorolac 15mg IV Versus 30mg IV on Duration of Analgesia in Patients Who Present to the Emergency Department With Renal Colic

What this Trial Is About

Researchers are evaluating how different doses of ketorolac affect pain relief duration in adults with suspected renal colic who visit the emergency department. This study focuses on comparing 15 mg versus 30 mg intravenous ketorolac to determine which dose provides longer-lasting pain control, especially noting that previous studies have not fully assessed ketorolac's peak analgesic effect at 120 minutes. The study is a prospective, randomized, triple-blind trial aiming to better understand optimal dosing for this common cause of emergency pain. Participants will be randomly assigned to receive either 15 mg or 30 mg of intravenous ketorolac. The study will monitor pain reduction at 120 minutes after dosing, with additional measurements at 90, 150, and 180 minutes. Researchers will also track if participants need extra pain medication and details about any additional analgesics used. The goal is to identify the dose that maintains effective pain relief while minimizing side effects. During the study, participants will have their pain evaluated at multiple time points using a pain scale. Researchers will collect information on the need for rescue pain medication and type and dose of such medication. The study includes adults aged 18 to 65 who present with moderate to severe pain associated with suspected renal colic. Participation involves receiving the study drug and undergoing pain assessments over several hours in the emergency department setting.

Evaluation of the Effects of Ketorolac Dose on Duration of Analgesia in Emergency Department (ED) Renal Colic Patients