Actively Recruiting

Phase 4
Age: 18Years +
All Genders
ID07225101

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

Led by University of Michigan · Updated on 2025-11-05

160

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

Sponsors

U

University of Michigan

Lead Sponsor

J

Johnson & Johnson

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the safety and long-term effects of the STRATAFIX suture device, which is already approved by the FDA for wound closures. This study focuses on people undergoing neurosurgical procedures on the brain or spine and aims to gather more information on how the body reacts to the STRATAFIX suture over time and its safety in closing surgical wounds. All participants will have their planned neurosurgical cranial or spine surgery with their wounds closed using the STRATAFIX PDS and Monocryl suture. This device uses barbed components to hold wound tension and is designed to be a long-lasting absorbable suture. The study does not include a comparison group, and all enrolled participants will receive the STRATAFIX suture treatment during their surgery. Participants will be monitored for wound healing and complications at 1, 3, and 6 months after surgery using tools such as the Bates-Jensen Wound Assessment Tool and Wound-Quality of Life questionnaires. Researchers will also track surgical site infections, patient satisfaction, wound imaging, and any need for wound revision. The time taken to close wounds and adherence to the suturing method will be recorded immediately after surgery. The study may last up to six months post-surgery for each participant.

CONDITIONS

Brief Title

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Elective or emergent surgical approaches for cranial or spine neurosurgical procedures requiring sutures for wound closure
  • Requirement for multilayer wound closure
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • History of prior surgical wound dehiscence or infection
  • Allergy to suture material

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Day of surgery

Participants undergo neurosurgical cranial or spine procedures with wound closure using STRATAFIX sutures.

1 visit (in-person)

Post-operative Follow-up

Duration - Up to 6 months

Participants are monitored for wound healing and complications after surgery.

Visits at 1, 3, and 6 months post-surgery

Trial Site Locations

Total: 1 location

1

University of Michigan Health Sparrow

Lansing, Michigan, United States, 48912

Actively Recruiting

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Research Team

K

Karen Sagher

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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