Actively Recruiting

Phase 2
Age: 18Years - 55Years
FEMALE
NCT05480995

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

Led by University of North Carolina, Chapel Hill · Updated on 2026-01-12

24

Participants Needed

1

Research Sites

184 weeks

Total Duration

On this page

Sponsors

U

University of North Carolina, Chapel Hill

Lead Sponsor

E

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Purpose: The aim of this study is to assess the sensitivity and specificity of FFNP PET/MRI for diagnosis of endometriosis. Participants: A total of 24 participants will be recruited from individuals with clinically suspected endometriosis. Procedures (methods): This is a prospective, one arm, single center study of 24 subjects with clinically suspected endometriosis to demonstrate FFNP PET-MRI's clinical utility for diagnosis of endometriosis.

CONDITIONS

Official Title

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

Who Can Participate

Age: 18Years - 55Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older
  • Female of childbearing age (18-55 years)
  • Clinically suspected (symptomatic) endometriosis as defined by referring physician
  • Scheduled for planned operative laparoscopy with no hormone treatment for at least two cycles
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Male
  • Institutionalized subject (prisoner or nursing home patient)
  • Known history of breast, ovarian or endometrial cancer
  • Pregnant or breast-feeding women
  • Chronic progestin-containing medications or Gonadotropin-releasing hormone (GnRH) analogues in the last 10-16 days or inability to discontinue these medications
  • Allergy to gadolinium contrast or Glomerular Filtration Rate (GFR) below 30 ml/min

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States, 27599

Actively Recruiting

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Research Team

M

Markeela Lipscomb, CCRC

CONTACT

H

Hannah Mignosa-Martin

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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