Pilot Study on the Effect of Potassium Sorbate on Food Intake and Body Weight in Obese Adults

What this Trial Is About

Researchers are studying how certain food additives might affect body weight in adults with obesity. This pilot randomized controlled trial aims to test the feasibility of measuring food consumption over 24 hours after a single administration of potassium sorbate compared to a placebo. Participants will first reduce their intake of related food additives to better observe any effects. The study involves two testing sessions where participants receive either a one-time 450 mg dose of potassium sorbate with breakfast followed by a washout period and then a placebo dose, or vice versa. Each washout period lasts at least two weeks between sessions. This crossover design allows participants to serve as their own controls. Participants will be monitored for recruitment, randomization, and retention rates during the 15-week active trial period. Dietary adherence is assessed through 24-hour dietary recalls for about two weeks after randomization. Researchers will also track any adverse events from randomization until study completion. The study is expected to end by June 2026.

Evaluation of Food Additive Contributions to Obesity: Pilot Study 1