Actively Recruiting
Evaluation of Fractalkine and Its Receptor in the Non-Surgical Treatment of Peri-implantitis
Led by Kubilay BARIŞ · Updated on 2024-11-12
100
Participants Needed
1
Research Sites
1 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating different non-surgical treatments for peri-implantitis, a condition affecting the tissues around dental implants. This study compares the effectiveness of mechanical debridement, Er:YAG laser treatment, and diode laser treatment in reducing the depth of peri-implant sulcus, which is an important measure for this condition. The study sponsor is Kubilay Barış. Participants will be divided randomly into groups: a healthy control group with no intervention, a group receiving mechanical debridement once, a group receiving Er:YAG laser decontamination three times, and a group receiving diode laser decontamination three times. These treatments aim to address inflammation and bone loss around the implants. During the study, participants will be monitored for changes in probing depth and clinical attachment loss after six months. Additional measures include gingival index, plaque index, and sulcus bleeding index to assess gum health. The study runs from November 2024 to May 2025 and involves regular assessments to track treatment effects and safety.
CONDITIONS
Brief Title
Evaluation of Fractalkine and Its Receptor in Peri-implantitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Probing depth of 4-6 mm, bone loss of at least 2 mm on X-ray and presence of inflammatory symptoms in soft tissue
- No systemic disease that may affect the outcome of the treatment
- Patients with healthy periodontium or patients with completed periodontal treatment
- Individuals at least 6 months after prosthesis loading on the implant
- Individuals who do not require further surgery for the treatment of peri-implantitis
- Implants with at least 2 mm keratised gingiva
- Individuals aged 40-60 years
You will not qualify if you...
- Individuals undergoing radiation therapy
- Individuals who smoke and drink alcohol
- Individuals in pregnancy or lactation
- Individuals who have received antibiotic treatment in the last three months
- Individuals with parafunctional habits
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Over several sessions as scheduled
Participants receive one session of subgingival debridement and three sessions of laser decontamination or mechanical debridement depending on their group assignment.
4 visits (in-person)
Duration - 6 months
Participants are monitored for treatment outcomes including probing depth and clinical attachment loss, gingival index, plaque index, and sulcus bleeding index.
Periodic visits for assessments up to 6 months
Trial Site Locations
Total: 1 location
1
Kırıkkale University, Faculty of Dentistry, Department of Periodontology
Kirikkale, Turkey (Türkiye), 71000
Actively Recruiting
Research Team
K
Kubilay Barış, Dr.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
4
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