Actively Recruiting

Phase Not Applicable
Age: 18Years - 42Years
FEMALE
Healthy Volunteers
NCT07187934

EVALUATION OF A FULLY AUTOMATED AI TOOL FOR EMBRYO RANKING

Led by Universitair Ziekenhuis Brussel · Updated on 2025-12-23

1325

Participants Needed

1

Research Sites

198 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to investigate whether embryo ranking by a fully automated AI tool (iDAScore) results in a similar transfer-to-pregnancy compared to manual embryo ranking by an embryologist. IVF patients who are planned for a freeze-all approach (where all usable embryos are frozen and transferred in later transfer cycles) will be allocated to either the control (ranking by embryologist) or intervention arm (ranking by iDAScore). The frozen embryos will be warmed and transferred one by one, according to their assigned rank. We want to see if the average number of embryo transfers that is needed to achieve a clinical pregnancy (transfer-to-pregnancy) is similar in both groups.

CONDITIONS

Official Title

EVALUATION OF A FULLY AUTOMATED AI TOOL FOR EMBRYO RANKING

Who Can Participate

Age: 18Years - 42Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients undergoing an ICSI/IVF treatment (with donor or own oocytes) planned for a freeze-all strategy on day 5
  • All types of sperm samples allowed (ejaculated or testicular, fresh or frozen, partner or donor origin)
  • At least 8 follicles (≥ 12 mm) on last follicular measurement before oocyte retrieval
  • Age between 18 and 42 years
  • Body mass index (BMI) between 18 and 35 kg/m²
  • Maximum of three IVF/ICSI cycles
  • Participants can only be included once in the trial
Not Eligible

You will not qualify if you...

  • Embassy patients
  • Use of frozen oocytes
  • In vitro maturation (IVM) cycles
  • Pre-implantation genetic testing (PGT) cycles
  • Proven untreated intra-uterine pathologies (e.g., Asherman syndrome, adenomyosis)
  • Endometriosis stage 3 or 4

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Brussels IVF, UZ Brussel

Brussels, Brussels Capital, Belgium, 1090

Actively Recruiting

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Research Team

E

Elsie Nulens

CONTACT

T

Tine Bosman, Msc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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