Actively Recruiting
Evaluation of 68-GaNOTA-Anti-HER2 VHH1 Uptake in Brain Metastasis of Cancer Patients
Led by Universitair Ziekenhuis Brussel · Updated on 2024-04-24
30
Participants Needed
1
Research Sites
476 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigates the uptake of the radiopharmaceutical 68-GaNOTA-Anti-HER2 VHH1 in brain metastasis using PET/CT imaging. Patients with HER2-positive and HER2-negative cancer will be included and the uptake in their lesions will be compared. Optional 68-GaNOTA-Anti-HER2 VHH1 scans may be performed during or after treatment, at time points 12±6 weeks and 24±9 weeks after the first scan.
CONDITIONS
Official Title
Evaluation of 68-GaNOTA-Anti-HER2 VHH1 Uptake in Brain Metastasis of Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients who have given informed consent
- Age 18 years or older
- Patients with brain metastasized cancer, with at least 1 brain lesion of at least 8 mm maximal diameter, as measured by CT or MRI
- Patients with potentially HER2-positive cancer, either with prior HER2 staining or sufficient tissue available for HER2 staining for study purposes
You will not qualify if you...
- Pregnant patients
- Breastfeeding patients
- Patients with recent (less than 1 week) gastrointestinal disorders with diarrhea as the major symptom
- Patients with any serious active infection
- Patients with any other life-threatening illness or organ system dysfunction that could compromise safety or interfere with evaluation
- Patients unable to communicate reliably with the investigator
- Patients at increased risk of death from a pre-existing concurrent illness
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Uz Brussel
Brussels, Belgium, 1090
Actively Recruiting
Research Team
U
UZ Brussel
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
0
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