Actively Recruiting

Phase Not Applicable
Age: 14Years +
All Genders
NCT05587751

Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients

Led by Mayo Clinic · Updated on 2025-05-09

44

Participants Needed

1

Research Sites

230 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this research study is to evaluate whether undergoing gender affirming care will impact the way the lungs function.

CONDITIONS

Official Title

Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients

Who Can Participate

Age: 14Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects speaking any language
  • Able to provide informed consent or have parental/guardian consent if under 18
  • Able to perform pulmonary function test maneuvers according to laboratory protocol
  • Enrolled through Mayo Clinic Rochester Transgender and Intersex Specialty Care Clinic
  • Decided to undergo hormonal gender-affirming therapies such as pubertal blockers or masculinizing/feminizing hormone therapies
Not Eligible

You will not qualify if you...

  • Unable to provide consent or unwilling to discuss the study with parents/guardians
  • Contraindications for pulmonary function testing including recent surgeries (<3 months) affecting lungs: abdominal, eye, thoracic, ear, brain, vascular surgery
  • Known respiratory disorders such as recent pulmonary embolism (<6 months), pleural effusion, pneumothorax, hemoptysis
  • Recent myocardial infarction (<1 month), new cardiac arrhythmia (<3 months), recent cardiac pacemaker implantation (<3 months)
  • Symptoms of heart failure, significant shortness of breath, tachycardia, or angina
  • Chronic pulmonary diseases affecting lung function such as asthma, chronic obstructive pulmonary disease, or interstitial lung diseases

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

K

Kayla Quinn, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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Evaluation of Gender-Affirming Treatments on Pulmonary Function in Transgender and Gender Diverse Patients | DecenTrialz