Actively Recruiting

Age: 18Years - 60Years
All Genders
ID07389863

Evaluation of Gynecological and Sexual Sequelae in Patients Treated for Rectal Cancer

Led by University Hospital, Rouen · Updated on 2026-05-05

15

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Rectal cancer represents about 40% of colorectal cancers, with around 15,000 new cases annually in France and a 5-year survival rate of 55% across all stages. Treatment usually involves surgical removal of the rectum, often combined with preoperative chemoradiotherapy and sometimes immunotherapy based on tumor characteristics. While these treatments improve recurrence-free survival, they can cause long-term complications affecting the digestive, urinary, gynecological, and sexual systems due to anatomical changes and nerve damage. This observational study focuses on women treated for rectal cancer, specifically evaluating the prevalence and features of gynecological and sexual side effects after their treatment. Data are collected through questionnaires including FSFI, QLQ-CR29, QLQ-C30, and the GynéRect questionnaire during a single follow-up visit. The study aims to better understand these side effects to improve prevention, assessment, and management, ultimately optimizing patients' quality of life. Participants will complete questionnaires assessing sexual dysfunction and gynecological sequelae during one follow-up visit. Researchers will analyze these responses to determine the prevalence and characteristics of these issues, identify risk factors, and evaluate the usefulness of the GynéRect questionnaire. The study measures the impact of these sequelae on overall quality of life, with involvement lasting a single day for data collection and evaluation.

CONDITIONS

Brief Title

Evaluation of Gynecological and Sexual Sequelae

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 18 to 60 at the time of diagnosis
  • Treated for rectal cancer between 2020 and 2025
  • Cancer is in remission
  • Sexually active before rectal cancer treatment
  • Completed required questionnaires during treatment
Not Eligible

You will not qualify if you...

  • Unable to complete questionnaires due to cognitive impairment or language barrier
  • Pregnant women
  • Women with active cancer or currently undergoing chemotherapy
  • History of extensive gynecological surgery
  • Under legal protection, guardianship, curatorship, or deprived of liberty
  • Without social security coverage

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Surveillance

Duration - 1 day

Participants complete questionnaires to assess gynecological and sexual sequelae after treatment for rectal cancer.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Service de Chirurgie Digestive

Rouen, France, 76031

Actively Recruiting

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Research Team

N

Nabila NL LAAJAIL, Director

V

vincent VF FERRANTI, ARC

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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