Actively Recruiting
Evaluation of Gynecological and Sexual Sequelae
Led by University Hospital, Rouen · Updated on 2026-05-05
15
Participants Needed
1
Research Sites
81 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Rectal cancer accounts for approximately 40% of colorectal cancers. In France, there are 15,000 new cases per year, and the 5-year survival rate is 55% across all stages. Treatment involves surgical resection of the rectum, often combined with preoperative chemoradiotherapy and sometimes immunotherapy, depending on the tumor's immunohistochemical status. This treatment strategy has improved recurrence-free survival but is associated with long-term functional complications affecting the digestive, urological, gynecological, and sexual systems. Surgery causes anatomical changes and damage to the autonomic nervous system plexuses. Radiotherapy, for its part, causes pelvic inflammation with the development of fibrosis and potential vascular and nerve damage. Various disorders can arise as a result of these anatomical changes, such as erectile dysfunction in men; dyspareunia and vaginal dryness in women; urinary incontinence and impaired sexual quality of life in both sexes.
CONDITIONS
Official Title
Evaluation of Gynecological and Sexual Sequelae
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 to 60 at the time of diagnosis
- Treated for rectal cancer between 2020 and 2025
- Cancer currently in remission
- Sexually active before treatment for rectal cancer
- Completed questionnaires during their treatment
You will not qualify if you...
- Unable to complete questionnaires due to cognitive impairment or language barrier
- Pregnant women
- Women with active cancer or undergoing chemotherapy
- History of extensive gynecological surgery
- Legally protected individuals or those deprived of liberty by judicial decision
- Individuals without social security coverage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service de Chirurgie Digestive
Rouen, France, 76031
Actively Recruiting
Research Team
N
Nabila NL LAAJAIL, Director
CONTACT
V
vincent VF FERRANTI, ARC
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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