Actively Recruiting
Evaluation of Gynecological and Sexual Sequelae in Patients Treated for Rectal Cancer
Led by University Hospital, Rouen · Updated on 2026-05-05
15
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Rectal cancer represents about 40% of colorectal cancers, with around 15,000 new cases annually in France and a 5-year survival rate of 55% across all stages. Treatment usually involves surgical removal of the rectum, often combined with preoperative chemoradiotherapy and sometimes immunotherapy based on tumor characteristics. While these treatments improve recurrence-free survival, they can cause long-term complications affecting the digestive, urinary, gynecological, and sexual systems due to anatomical changes and nerve damage. This observational study focuses on women treated for rectal cancer, specifically evaluating the prevalence and features of gynecological and sexual side effects after their treatment. Data are collected through questionnaires including FSFI, QLQ-CR29, QLQ-C30, and the GynéRect questionnaire during a single follow-up visit. The study aims to better understand these side effects to improve prevention, assessment, and management, ultimately optimizing patients' quality of life. Participants will complete questionnaires assessing sexual dysfunction and gynecological sequelae during one follow-up visit. Researchers will analyze these responses to determine the prevalence and characteristics of these issues, identify risk factors, and evaluate the usefulness of the GynéRect questionnaire. The study measures the impact of these sequelae on overall quality of life, with involvement lasting a single day for data collection and evaluation.
CONDITIONS
Brief Title
Evaluation of Gynecological and Sexual Sequelae
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Women aged 18 to 60 at the time of diagnosis
- Treated for rectal cancer between 2020 and 2025
- Cancer is in remission
- Sexually active before rectal cancer treatment
- Completed required questionnaires during treatment
You will not qualify if you...
- Unable to complete questionnaires due to cognitive impairment or language barrier
- Pregnant women
- Women with active cancer or currently undergoing chemotherapy
- History of extensive gynecological surgery
- Under legal protection, guardianship, curatorship, or deprived of liberty
- Without social security coverage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 day
Participants complete questionnaires to assess gynecological and sexual sequelae after treatment for rectal cancer.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Service de Chirurgie Digestive
Rouen, France, 76031
Actively Recruiting
Research Team
N
Nabila NL LAAJAIL, Director
V
vincent VF FERRANTI, ARC
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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