Actively Recruiting
Evaluation of IL 12B Genetic Polymorphism (rs3213094)
Led by South Valley University · Updated on 2025-08-19
40
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Psoriasis is a skin disorder that is chronic proliferative and inflammatory in nature. Extensor surfaces, scalp, and lumbosacral area are covered in erythematous plaques with silvery scales. The disease can also impair the eyes and joints. It has no cure. Because of their low quality of life, many psoriasis patients experience depression. In addition to the cutaneous manifestations, it is associated with an increased risk of psoriatic arthritis, depression and cardiovascular disease.
CONDITIONS
Official Title
Evaluation of IL 12B Genetic Polymorphism (rs3213094)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with psoriasis clinically for at least 6 months
- Severe psoriasis defined as a Psoriasis Area and Severity Index (PASI) score greater than 10
- Psoriasis involving more than 10% of the body surface area
- Presence of psoriatic arthritis
You will not qualify if you...
- Patients with other autoimmune or inflammatory diseases such as rheumatoid arthritis or lupus
- Pregnant or breastfeeding women
- Patients currently receiving treatments other than Humira
- Known genetic disorders affecting the immune system
- Patients treated with therapies other than Humira in the last 6 months
- Active infections including tuberculosis or chronic viral infections like hepatitis B, hepatitis C, or HIV
- Contraindications to Humira
- Renal and vascular diseases
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Qina University hospital, South Valley University Hospital
Qina, Egypt
Actively Recruiting
Research Team
A
Alaa Ahmed Saad Ali Aweida, MSc
CONTACT
S
Soheir Abdel-Hamid Ali, Lecturer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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