Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06980012

Evaluation of the Impact of the Clinical Pharmacist in the Initiation and Follow-up of Oral Therapies in Oncology

Led by Polyclinique Lyon Nord · Updated on 2025-08-26

90

Participants Needed

1

Research Sites

13 weeks

Total Duration

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AI-Summary

What this Trial Is About

Researchers are evaluating the role of hospital pharmacists at the start of oral cancer treatments taken at home. This study aims to see how pharmaceutical monitoring at treatment initiation affects patient adherence, management of side effects, and overall treatment follow-up. The focus is on patients with solid tumors who begin oral therapy for cancer, excluding blood cancers. Participants are randomly assigned to one of two groups: one receiving a specialized pharmaceutical consultation at the hospital plus follow-up communication between hospital and community pharmacists, and the other receiving only the initial pharmaceutical consultation. The follow-up includes contacting the patient's local pharmacy to ensure treatment continuity and monitoring for issues such as missed refills or side effects. This approach compares standard pharmaceutical consultation with enhanced monitoring and coordination. During the study, patients will be assessed for treatment adherence at 3 and 6 months using the Girerd questionnaire. Researchers will track side effect management and treatment continuation through records kept by the pharmacists. The study emphasizes collaboration between hospital and community pharmacies to support patients throughout their oral cancer therapy. Participation involves regular monitoring and follow-up over several months to evaluate compliance and optimize care.

CONDITIONS

Brief Title

Evaluation of the Impact of the Clinical Pharmacist in Oral Therapies in Oncology.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient suffering from an oncological pathology (excluding hematological malignancies)
  • Starting oral cancer treatment taken at home, either new or started less than 30 days ago
  • Oral therapy dispensed through a pharmacy
  • Patient able to continue oral therapy dispensed in pharmacies
Not Eligible

You will not qualify if you...

  • Patients with hematological malignancies
  • Patients living in a hospital or care institution
  • Patients treated for more than 30 days
  • Patients receiving cancer treatment other than oral therapy (such as intravenous or subcutaneous treatments)
  • Patients whose treatment after initiation is not dispensed in a pharmacy or community setting

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit (in-person)

Treatment

Duration - Up to 6 months after treatment initiation

Participants receive specialized pharmaceutical consultation at the start of their oral cancer treatment, followed by ongoing follow-up consultations to support treatment adherence and manage any issues.

Initial consultation at treatment start and follow-up contacts around each treatment renewal

Follow-up

Duration - Up to 6 months after treatment initiation

Participants are observed for treatment adherence and clinical outcomes up to 6 months after starting oral therapy.

Assessments at 3 months and 6 months after treatment initiation

Trial Site Locations

Total: 1 location

1

Polyclinique Lyon Nord

Rillieux-la-Pape, France

Actively Recruiting

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Research Team

M

Marion Mandon, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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