Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT05241405

Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast or Gynecological Cancer

Led by Centre Francois Baclesse · Updated on 2024-10-01

354

Participants Needed

10

Research Sites

257 weeks

Total Duration

On this page

Sponsors

C

Centre Francois Baclesse

Lead Sponsor

N

NATSUCA laboratory

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a multicenter randomized trial in breast cancer patients reporting cancer-related fatigue to evaluate the efficacy and safety of Qiseng® based on extract of American ginseng combined with vitamin C from extract of Camu Camu berries

CONDITIONS

Official Title

Evaluation of the Impact of Taking American Ginseng for 8 Weeks on Fatigue in Patients Treated for Localized Breast or Gynecological Cancer

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with localized breast or gynecological cancer treated with curative adjuvant and/or neoadjuvant chemotherapy and/or adjuvant radiotherapy completed within 6 months
  • Chronic, stable fatigue with a score of 4 or higher on a 10-point scale lasting at least one month
  • Allowed maintenance hormone or other therapies except pembrolizumab, abemaciclib, and PARP inhibitors
  • Women aged 18 years or older
  • Effective contraception for women of childbearing age
  • Affiliated with a social security plan
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Other causes of fatigue such as anemia grade > 2 or chronic diseases linked to fatigue
  • Ongoing chemotherapy (except oral capecitabine or trastuzumab-emtasin in adjuvant setting)
  • Metastatic breast or gynecological cancer
  • Treatment with tyrosine kinase inhibitors, P-gp transported molecules, pembrolizumab, or PARP inhibitors
  • Requirement for oral diabetes therapy
  • Regular vitamin C intake beyond diet
  • Chronic pain needing daily analgesics, anti-inflammatory drugs, or corticosteroids
  • Use of ginseng products in the month before inclusion
  • Hypersensitivity to Qiseng or placebo components
  • Pregnant or breastfeeding
  • Participation in other experimental therapeutic trials
  • Legal restrictions such as deprivation of liberty, guardianship, or curatorship
  • Inability to follow medical monitoring due to geographical, social, or psychological reasons
  • History of malignant disease in last 3 years except certain skin and uterine cancers and treated solid tumors or lymphomas without recurrence for at least 3 years

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 10 locations

1

ARCOCEA_Clinique Europe

Amiens, France

Not Yet Recruiting

2

Ch Bayeux

Bayeux, France

Not Yet Recruiting

3

Centre Pierre Curie

Beuvry, France

Not Yet Recruiting

4

Centre François Baclesse

Caen, France

Actively Recruiting

5

Polyclinique du Parc

Caen, France

Not Yet Recruiting

6

Ch Calais

Calais, France

Actively Recruiting

7

Ch Cherbourg

Cherbourg, France

Not Yet Recruiting

8

Clinique de Flandre

Coudekerque-Branche, France

Actively Recruiting

9

Centre Henri Becquerel

Rouen, France

Actively Recruiting

10

Clinique des Dentellières

Valenciennes, France

Actively Recruiting

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Research Team

C

Carine SEGURA, MD

CONTACT

A

Alexandra LECONTE

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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