Actively Recruiting
Evaluation and Implementation Preparation of a Proactive Palliative Care Model (ENABLE-SG)
Led by National Cancer Centre, Singapore · Updated on 2026-04-30
715
Participants Needed
1
Research Sites
192 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The current interdisciplinary specialist palliative care model focuses on supporting patients with advanced cancer who have complex problems in the last weeks of life. Consequently, palliative care is often provided late and in response to uncontrolled symptoms during crises. Palliative care models should shift from this reactionary illness-stress paradigm to a proactive health-wellness approach that is integrated early in the patient's disease trajectory. A proactive early palliative care telehealth model, ENABLE (Educate, Nurture, Advise, Before Life Ends), was developed in the U.S. to coach patients with advanced cancers and their family caregivers on how to cope effectively with serious illness. By empowering individuals early before acute distress and symptoms occur, patients and families can better mitigate and avoid crises. Building on positive health outcomes demonstrated by the ENABLE model in the U.S., the study team has successfully pilot-tested a culturally adapted ENABLE-SG model in Singapore. This study seeks to test the effectiveness of this ENABLE-SG model among patients with recently diagnosed advanced cancer and their caregivers while simultaneously collecting data on real-world implementation.
CONDITIONS
Official Title
Evaluation and Implementation Preparation of a Proactive Palliative Care Model (ENABLE-SG)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 21 or older
- Patients diagnosed within 60 days with advanced cancer (metastatic or recurrent/progressive Stage III/IV solid tumour)
- Able to speak English or Chinese
- Able to provide informed consent
- Caregivers aged 21 or older
- Caregivers identified by patient as unpaid spouse/partner, relative, or friend providing at least 7 hours of support weekly
- Caregivers caring for a patient with advanced cancer
- Caregivers able to speak English or Chinese
- Caregivers able to provide informed consent
- Healthcare professionals aged 21 or older
- Healthcare professionals approached to participate and able to provide informed consent
You will not qualify if you...
- Patients with active severe mental illness, dementia, active suicidal ideation, or uncorrected hearing loss
- Patients unable to complete patient-reported outcome measures
- Patients previously reviewed by palliative care services under the current model
- Caregivers with self-reported severe mental illness, dementia, active suicidal ideation, or uncorrected hearing loss
- Caregivers unable to complete caregiver-reported outcomes
- Healthcare professionals not providing care for cancer patients
- Healthcare professionals unable to complete study interviews
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
National Cancer Centre Singapore
Singapore, Singapore, 168583
Actively Recruiting
Research Team
G
Grace M Yang, MRCP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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