Actively Recruiting
Evaluation of an Intensive Training Program for Patients with Hereditary Spastic Paraparesis SPG4/Spast
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2024-11-25
50
Participants Needed
1
Research Sites
130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Hereditary spastic paraparesis is a group of inherited neurological diseases. Only symptomatic treatments exist for the moment. The Modifspa study (cf citation) carried out by the team showed that patients perceived a feeling of effectiveness of physiotherapy on lower limb spasticity. The aim of the Walk-up study is to objectivize this feeling of efficacy on gait disorders in these patients. This is an interventional study using physical training. The study is prospective, open, randomized in 2 parallel groups, one of which is a control group. Analyses will be comparative between the 2 groups during the course of the study.
CONDITIONS
Official Title
Evaluation of an Intensive Training Program for Patients with Hereditary Spastic Paraparesis SPG4/Spast
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with molecular diagnosis of hereditary spastic paraparesis based on pathogenic variant of SPAST gene
- Able to walk for 6 minutes without human assistance, with or without technical aids such as cane, walker, or orthoses
- Receiving at least 1 physiotherapy session per week
- Able to understand the study protocol
- Has access to the internet at home to use video materials provided in the study
You will not qualify if you...
- Botulinum toxin injection within 2 months before joining the study
- Stopped private physiotherapy
- Refuses to participate in the study
- Participating in another interventional clinical trial or randomized clinical trial
- Pregnant women
- Not covered by or beneficiary of a social security scheme
- Under legal guardianship or trusteeship
AI-Screening
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Trial Site Locations
Total: 1 location
1
ICM, Hôpital Pitié-Salpêtrière
Paris, France, 75013
Actively Recruiting
Research Team
P
Pauline Lallemant, MD
CONTACT
R
Rania Hilab, CRA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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