Actively Recruiting
Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks
Led by Kafrelsheikh University · Updated on 2026-01-26
20
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to compare the feasibility and effectiveness of using an internal nasal splint- supported free graft versus a nasoseptal flap alone for endoscopic repair of bilateral CSF leaks. Research question: Does the use of an internal nasal splint to support a free graft during endoscopic repair of bilateral CSF leaks improve outcomes compared to the use of a nasoseptal flap alone?
CONDITIONS
Official Title
Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 18 years or older
- Patients with bilateral cerebrospinal fluid (CSF) leaks confirmed by imaging and biochemical testing (e.g., beta-2 transferrin)
- Patients with bilateral CSF leaks and severe septal spur
- Patients with bilateral CSF leaks and history of submucosal resection of nasal septum
- Patients with bilateral CSF leaks and large septal perforation
- Patients with bilateral CSF leaks and septal granuloma
You will not qualify if you...
- Patients with contraindications to endoscopic surgery
- Patients with active sinus or nasal infections
- Patients with previous nasal or skull base surgery affecting the repair site
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Kafrelsheikh Faculty of Medicine
Kafr Elsheikh, Kafrelsheikh, Egypt, 33155.
Actively Recruiting
Research Team
A
Amr Maher Shady, resident
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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