Assessing Heart Function to Predict Successful Breathing Support Removal in Adult ICU Patients Using Echocardiography

What this Trial Is About

Researchers are evaluating whether measurements of left ventricular function using transthoracic echocardiography TTE can predict the success of weaning adult intensive care unit ICU patients from mechanical ventilation. The study focuses on several heart function parameters, including Left Ventricular Outflow Tract Velocity Time Integral LVOT VTI, Mitral Annular Plane Systolic Excursion MAPSE, Ee ratio, EA ratio, Mitral Deceleration Time MDT, and Myocardial Performance Index Tei index. The goal is to understand how heart function affects the ability to stop ventilator support and improve ICU care decisions. Adult ICU patients who are on mechanical ventilation and meet weaning criteria will receive a standardized transthoracic echocardiographic exam within 2 hours. During this exam, the study team will measure the heart function parameters listed above. After this assessment, patients will be monitored for 24 hours following extubation to see if they remain off ventilatory support, including checking for any need for reintubation, non-invasive ventilation, or high-flow oxygen therapy. Participants will be closely observed during the 24 hours after extubation to determine if they successfully maintain spontaneous breathing without ventilator assistance. The study will collect echocardiographic data and clinical follow-up information to analyze the predictive value of heart function measures on weaning outcomes. This research may help guide more precise and physiologically based decisions about when and how to wean patients from mechanical ventilation, potentially reducing complications and optimizing ICU resource use.

Evaluation of Left Ventricular Function to Predict Weaning Success in the Intensive Care Unit