Actively Recruiting
Evaluation of Long-Acting Injectable (LAI) and Teen Clubs in Adolescents (ATTUNE).
Led by Africa Health Research Institute · Updated on 2026-04-03
720
Participants Needed
12
Research Sites
176 weeks
Total Duration
On this page
Sponsors
A
Africa Health Research Institute
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This is a 2-stage study assessing the effect of peer navigation (support from peers) and long-acting injectable antiretroviral therapy (ART) on viral suppression and retention in care among adolescents living with HIV and receiving care in South Africa.
CONDITIONS
Official Title
Evaluation of Long-Acting Injectable (LAI) and Teen Clubs in Adolescents (ATTUNE).
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 12 and less than 19 years at enrollment
- Living with HIV
- Aware of their HIV status
- Receiving antiretroviral therapy (ART) for at least six months
- Able to read and/or speak English, isiZulu, Sepedi, Afrikaans, Xhosa, or Sesotho
- Willing and able to consent to study activities
- Willing and able to obtain parental consent for study activities
- (Stage 1, objective 2 only) Age 18 years or older and caregiver of an adolescent with HIV
- (Stage 1, objective 2 only) Age 18 years or older and provides clinical services or is a policy maker involved in adolescents with HIV
You will not qualify if you...
- Unable to read and/or speak English, isiZulu, Sepedi, Afrikaans, Xhosa, or Sesotho
- Severe mental or physical illness preventing participation in informed consent activities
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 12 locations
1
Charlotte Maxeke Hospital
Johannesburg, Gauteng, South Africa, 2001
Actively Recruiting
2
Rahima Moosa Mother and Child Hospital
Johannesburg, Gauteng, South Africa, 2001
Actively Recruiting
3
Kgabo CHC
Pretoria, Gauteng, South Africa, 0001
Not Yet Recruiting
4
KT Motubatse CHC
Pretoria, Gauteng, South Africa, 0001
Not Yet Recruiting
5
Soshanguve Block JJ
Pretoria, Gauteng, South Africa, 0001
Not Yet Recruiting
6
Soshanguve Block TT
Pretoria, Gauteng, South Africa, 0001
Not Yet Recruiting
7
Cato Manor CHC
Durban, KwaZulu-Natal, South Africa, 4001
Actively Recruiting
8
KwaMashu CHC
Durban, KwaZulu-Natal, South Africa, 4001
Actively Recruiting
9
Mtubatuba CHC
Mtubatuba, KwaZulu-Natal, South Africa, 3935
Actively Recruiting
10
Somkhele CHC
Mtubatuba, KwaZulu-Natal, South Africa, 3935
Actively Recruiting
11
Eerste River Hospital
Cape Town, Western Cape, South Africa, 8001
Not Yet Recruiting
12
Michael Mapongwana CHC
Cape Town, Western Cape, South Africa, 8001
Not Yet Recruiting
Research Team
D
Dr Moherndran Archary, MBChB, PhD
CONTACT
L
Leora Sewnarain, HDE
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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