Actively Recruiting
Evaluation of the Effects of Different Rapid Maxillary Expansion Methods on the Nasomaxillary Complex Structures
Led by Merve Kulaksız · Updated on 2026-01-08
30
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Maxillary transverse deficiency is a condition where the upper and lower dental arches do not align properly due to a narrow maxilla. This condition can cause symptoms such as crossbite, crowded teeth, and breathing difficulties. Causes include genetic factors, early loss of baby teeth, mouth breathing, thumb sucking, and abnormal swallowing. Treatment depends on age and suture closure, with rapid or slow palatal expansion used in younger patients and surgical or mini-screw-assisted methods preferred for adults due to bone rigidity. This study compares two treatments for maxillary transverse narrowing: mini-screw-assisted rapid palatal expansion (MARPE) and surgically assisted rapid maxillary expansion (SARME). Thirty patients will be divided into these groups based on their expansion needs and suture condition. The MARPE group will receive custom mini-screw devices placed under local anesthesia, while the SARME group will undergo surgery with an acrylic cap splint. Both groups will have their appliances removed after six months of retention. Participants will undergo cone beam computed tomography (CBCT) scans before treatment and after six months to measure changes in craniofacial volumes, canal dimensions, nasal breathing volume, and septal deviation. The study will assess volume, length, angle, and diameter changes in nasolacrimal and nasopalatine canals, maxillary sinus volume, and ostium openings. These evaluations aim to compare the effects of MARPE and SARME on the nasomaxillary complex structures over the treatment period.
CONDITIONS
Brief Title
Evaluation of Maxillary Expansion Methods on Nasomaxillary Structures
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of maxillary transverse deficiency
- Patients aged 15 years and older
- Presence of unilateral or bilateral crossbite
You will not qualify if you...
- Severe facial deformities or craniofacial syndromes
- History of previous orthodontic treatment
- Existing pathology or history of surgery related to the paranasal sinuses, nasolacrimal system, or orbital cavity
- Inadequate patient cooperation
- History of trauma, or previous maxillofacial/plastic surgery procedures
- Clinical signs or symptoms of maxillary sinus pathology (e.g., maxillary sinus cysts, sinusitis)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo placement of the expansion device. In the MARPE group, mini-screws are placed under local anesthesia. In the SARME group, participants undergo surgical maxillary expansion under general anesthesia.
1 visit (in-person)
Duration - Approximately 6 months including retention period
Participants receive active maxillary expansion using the assigned device or surgical procedure.
Regular visits during the 6-month retention period
Duration - At start and after 6 months
Participants undergo cone beam computed tomography (CBCT) scans before starting expansion treatment and after the 6-month retention period to assess changes in craniofacial structures.
2 visits (in-person)
Trial Site Locations
Total: 1 location
1
Bezmialem Vakif University Faculty of Dentistry, Department of Orthodontics
Istanbul, Fatih, Turkey (Türkiye), 34093
Actively Recruiting
Research Team
M
Merve Kulaksız, PhD Student
Ş
Şerife Şahin, Assistant Professor
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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