Actively Recruiting

Phase Not Applicable
Age: 15Years +
All Genders
ID07326345

Evaluation of the Effects of Different Rapid Maxillary Expansion Methods on the Nasomaxillary Complex Structures

Led by Merve Kulaksız · Updated on 2026-01-08

30

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Maxillary transverse deficiency is a condition where the upper and lower dental arches do not align properly due to a narrow maxilla. This condition can cause symptoms such as crossbite, crowded teeth, and breathing difficulties. Causes include genetic factors, early loss of baby teeth, mouth breathing, thumb sucking, and abnormal swallowing. Treatment depends on age and suture closure, with rapid or slow palatal expansion used in younger patients and surgical or mini-screw-assisted methods preferred for adults due to bone rigidity. This study compares two treatments for maxillary transverse narrowing: mini-screw-assisted rapid palatal expansion (MARPE) and surgically assisted rapid maxillary expansion (SARME). Thirty patients will be divided into these groups based on their expansion needs and suture condition. The MARPE group will receive custom mini-screw devices placed under local anesthesia, while the SARME group will undergo surgery with an acrylic cap splint. Both groups will have their appliances removed after six months of retention. Participants will undergo cone beam computed tomography (CBCT) scans before treatment and after six months to measure changes in craniofacial volumes, canal dimensions, nasal breathing volume, and septal deviation. The study will assess volume, length, angle, and diameter changes in nasolacrimal and nasopalatine canals, maxillary sinus volume, and ostium openings. These evaluations aim to compare the effects of MARPE and SARME on the nasomaxillary complex structures over the treatment period.

CONDITIONS

Brief Title

Evaluation of Maxillary Expansion Methods on Nasomaxillary Structures

Who Can Participate

Age: 15Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of maxillary transverse deficiency
  • Patients aged 15 years and older
  • Presence of unilateral or bilateral crossbite
Not Eligible

You will not qualify if you...

  • Severe facial deformities or craniofacial syndromes
  • History of previous orthodontic treatment
  • Existing pathology or history of surgery related to the paranasal sinuses, nasolacrimal system, or orbital cavity
  • Inadequate patient cooperation
  • History of trauma, or previous maxillofacial/plastic surgery procedures
  • Clinical signs or symptoms of maxillary sinus pathology (e.g., maxillary sinus cysts, sinusitis)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - 1 day

Participants undergo placement of the expansion device. In the MARPE group, mini-screws are placed under local anesthesia. In the SARME group, participants undergo surgical maxillary expansion under general anesthesia.

1 visit (in-person)

Treatment

Duration - Approximately 6 months including retention period

Participants receive active maxillary expansion using the assigned device or surgical procedure.

Regular visits during the 6-month retention period

Imaging Visits

Duration - At start and after 6 months

Participants undergo cone beam computed tomography (CBCT) scans before starting expansion treatment and after the 6-month retention period to assess changes in craniofacial structures.

2 visits (in-person)

Trial Site Locations

Total: 1 location

1

Bezmialem Vakif University Faculty of Dentistry, Department of Orthodontics

Istanbul, Fatih, Turkey (Türkiye), 34093

Actively Recruiting

Loading map...

Research Team

M

Merve Kulaksız, PhD Student

Ş

Şerife Şahin, Assistant Professor

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

Similar Trials

Three-Dimensional Evaluation of the Effects of Different Max...

Maxillary Transverse Deficiency

Actively Recruiting

1 location

3D-Printed Versus Laboratory-Fabricated Hyrax Expanders A Ra...

Maxillary Expansion

Actively Recruiting

2 locations

Three-dimensionally Printed Hyrax Versus Conventional Hyrax ...

Transverse Maxillary Deficiency

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here