Actively Recruiting

Age: 18Years +
All Genders
NCT06963853

Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis

Led by Western Galilee Hospital-Nahariya · Updated on 2025-05-14

200

Participants Needed

1

Research Sites

276 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This prospective study aims to evaluate the diagnostic value and reliability of blood cultures obtained from different sources-central venous catheter (CVC), dialysis machine, and peripheral vein-in hemodialysis patients with suspected catheter-related bloodstream infections (CRBSIs). By comparing the timing and rates of bacterial growth from each site, the study seeks to identify the most accurate and timely method for diagnosing bloodstream infections in this patient population. In addition, the study will assess the dynamics of parathyroid hormone (PTH) levels during acute infections. Specifically, it will investigate whether a significant drop in PTH levels-and the rate of recovery following infection-correlates with adverse outcomes such as infectious complications, cardiovascular morbidity, or 90-day mortality. These findings may offer valuable prognostic insights and support improved monitoring and treatment strategies for dialysis patients experiencing infection.

CONDITIONS

Official Title

Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

hemodialysis patients over the age of 18 who are hospitalized at the Galilee Medical Center due to sepsis and have provided written informed consent to participate in this study.

-

Not Eligible

You will not qualify if you...

• Patients with cognitive impairment who are unable to provide informed consent.

-

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Galilee Medical Center

Nahariya, Israel, Israel, 2210001

Actively Recruiting

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Research Team

E

Etty Kruzel-Davila, MD

CONTACT

O

Olga Vdovich, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Evaluation of Microbial and Endocrinological Parameters in Dialysis Patients With Sepsis | DecenTrialz