Study of Microcirculation Changes After Fluid Treatment in Critically Ill Patients with Venous Congestion

What this Trial Is About

This observational study focuses on critically ill patients in intensive care who show signs of venous congestion. Researchers aim to evaluate how these patients microcirculatory status changes after receiving fluids compared to those without venous congestion. The main question is whether fluid-responsive patients with venous congestion experience worsening microcirculation following fluid administration. Participants will undergo a fluid challenge after initial assessment of venous congestion signs and microcirculation. Microcirculatory measures, including total vessel density and perfused vessel density, will be recorded at baseline, immediately after the fluid challenge, and again 30 minutes later. The study does not involve a drug intervention but uses a fluid challenge as the key procedure. During the study, participants will have sublingual microcirculation monitored using various indices at three time points around the fluid challenge. Researchers will analyze changes in these microcirculatory parameters and their association with venous congestion. The study will continue through June 2026, with assessments focused on understanding microcirculatory responses in this critical care setting.

Evaluation of the Microcirculatory Response to Fluids in Critically Ill Patients With Venous Congestion: A Prospective Observational Study