Actively Recruiting

Phase Not Applicable
Age: 45Years +
All Genders
Healthy Volunteers
NCT06523868

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study

Led by Dana-Farber Cancer Institute · Updated on 2026-02-27

1500

Participants Needed

1

Research Sites

182 weeks

Total Duration

On this page

Sponsors

D

Dana-Farber Cancer Institute

Lead Sponsor

U

United States Department of Defense

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this research study is to evaluate the possible benefits of an investigational, but commercially available Galleri multi-cancer early detection (MCED) blood test which is designed to detect many types of cancer early in veterans who have served in the military in active duty. The name of the screening blood test being studied is: -GRAIL Galleri MCED test

CONDITIONS

Official Title

Evaluation of Multi-Cancer Early Detection Testing in a High-Risk Military Population: The Sentinel Study

Who Can Participate

Age: 45Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Active-duty or National Guard/Reserves military service for four or more years
  • Age 45 or older
  • Received care at a VA facility within past 5 years
  • Able to sign informed consent
  • Willingness to travel to Dana-Farber Cancer Institute in Boston, MA, for diagnostic testing if screening test indicates possible malignancy
Not Eligible

You will not qualify if you...

  • Diagnosed with invasive malignancy within 3 years of enrollment (non-melanoma skin cancer is acceptable)
  • Evidence of symptomatic or active cancer requiring therapeutic intervention at the time of participation (hormone therapy for breast/prostate cancer is acceptable)
  • Currently being evaluated for clinical suspicion of cancer

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

Dana-Farber Cancer Institute

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

E

Elizabeth ODonnell, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SCREENING

Number of Arms

1

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