Actively Recruiting

Age: 0Years - 15Years
All Genders
ID06087315

Realist Evaluation and Learning in a Multi-country Medical Oxygen Program to Improve Oxygen Access and Use in Children Under 15

Led by Murdoch Childrens Research Institute · Updated on 2025-06-15

1200

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

M

Murdoch Childrens Research Institute

Lead Sponsor

M

Makerere University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to understand how oxygen and pulse oximetry are used in healthcare facilities across multiple countries, focusing on children under 15 years old with conditions like hypoxemia, pneumonia, neonatal disease, sepsis, and mortality risks. The study addresses the critical issue of oxygen access disparities exacerbated by the COVID-19 pandemic and seeks to identify barriers and opportunities to improve oxygen systems for better patient care. It involves five mixed-methods sub-studies designed to explore facility readiness, care pathways, patient journeys, healthcare worker practices, and stakeholder perspectives in six countries. The study evaluates different multi-faceted oxygen system strengthening interventions tailored to each country's context. These include efforts to improve policies, governance, healthcare worker and technician training, and data systems for oxygen use and maintenance. The research uses a mixed methods design with sequential and concurrent data collection across sub-studies that involve cross-sectional assessments, direct observations, interviews, and focus groups in selected health facilities representing various performance levels. Participants, primarily children under 15 and healthcare staff, will be observed and interviewed to map care processes, oxygen use, and decision-making in emergency and inpatient settings. Data collection includes patient and equipment flow mapping, patient journey tracking during initial care hours, nursing practices, and stakeholder perceptions. The study will measure mixed methods outcomes over five years, aiming to inform effective policies and strategies to enhance oxygen access and use. The total study duration extends to December 2027, with ongoing monitoring and analysis.

CONDITIONS

Brief Title

Evaluation of a Multi-country Medical Oxygen Program

Who Can Participate

Age: 0Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children under 15 years old admitted to participating health facilities
  • Admitted with conditions such as hypoxemia, pneumonia, neonatal disease, sepsis, or related serious illness
  • Receiving care at facilities in the MOXY program countries: Nigeria, Uganda, Liberia, Rwanda, Cambodia, and Lao PDR
  • Willingness to participate in observations, interviews, and focus group discussions
  • Facilities selected represent a range of oxygen system performance levels and types of care
Not Eligible

You will not qualify if you...

  • Age 15 years or older
  • Not admitted to a participating health facility in the MOXY program
  • Unable or unwilling to participate in study procedures such as observations or interviews
  • Facilities outside the selected six MOXY program countries
  • Patients without conditions related to hypoxemia or the specified serious illnesses

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Concurrent with data collection over the study period

Participants undergo observations and interviews to understand oxygen system performance and care pathways in their health facilities.

Multiple observation and interview sessions depending on sub-study involvement

Long-term Monitoring

Duration - Up to 5 years

Participants are observed over time to evaluate the impact of oxygen system strengthening interventions on oxygen access and use in children under 15 years old.

Ongoing data collection through observations, interviews, and focus groups

Trial Site Locations

Total: 3 locations

1

10 Facilities to Be Selected

Phnom Penh, Cambodia

Actively Recruiting

2

10 Facilities to Be Selected

Ibadan, Nigeria

Active, Not Recruiting

3

10 Facilities to Be Selected

Kampala, Uganda

Active, Not Recruiting

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Research Team

R

Rami Subhi, FRACP

H

Hamish Graham, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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