Actively Recruiting

Phase Not Applicable
Age: 1Hour - 24Hours
All Genders
Healthy Volunteers
NCT06550219

Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound

Led by Alexandria University · Updated on 2025-02-04

30

Participants Needed

1

Research Sites

49 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effect of non-invasive ventilation (nIPPV) , (nCPAP), and nasal high flow cannula (NHFC) as a primary mode of ventilation in preterm neonates \<37 gestational week with moderate to severe RD using LUS as regard: I. Primary outcomes: Duration of non-Invasive ventilation. II. Secondary outcomes: Evaluation LUS over the 1 st 7 days of life or weaning from ventilation. Need for intubation and invasive ventilation. Duration of respiratory support. Need for surfactant. Oxygen saturation index and oxygen index. Broncho-pulmonary dysplasia; grade. Duration of hospital stay

CONDITIONS

Official Title

Evaluation of Nasal Non Invasive Ventilation in Management of Neonates With Respiratory Distress Using Lung Ultrasound

Who Can Participate

Age: 1Hour - 24Hours
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Preterm less than 37 weeks gestational age admitted to the NICU
  • Spontaneously breathing with signs of respiratory distress such as tachypnea, nasal flaring, chest retractions, or grunting
Not Eligible

You will not qualify if you...

  • Major congenital abnormalities
  • Intubation for resuscitation or other reasons
  • Need for invasive mechanical ventilation
  • Pulmonary hemorrhage
  • Severe cardiovascular instability
  • Cardiopulmonary arrest requiring prolonged resuscitation
  • Birth asphyxia with one-minute Apgar score 3 or less
  • Major cardiac diseases except patent ductus arteriosus

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Alexandria university, Elshattbi hospital

Alexandria, Egypt, 0354

Actively Recruiting

Loading map...

Research Team

M

Marwa M Farag, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here