Actively Recruiting
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia
Led by Neurocrine Biosciences · Updated on 2026-04-15
120
Participants Needed
2
Research Sites
75 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary objective for this study is to evaluate the efficacy of NBI-1117570 compared with placebo on improving behavioral and psychological symptoms of schizophrenia in adults who warrant inpatient hospitalization.
CONDITIONS
Official Title
Evaluation of NBI-1117570 in Inpatient Adults With Schizophrenia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 55 years
- Primary diagnosis of schizophrenia for at least 1 year before screening
- Experiencing an acute relapse or worsening of symptoms starting less than 2 months before screening
- Currently requires hospitalization for schizophrenia symptoms
- Positive response to at least one antipsychotic treatment (excluding clozapine) for a prior relapse
You will not qualify if you...
- Imminent risk of suicide or harm to self or others
- History of epilepsy, seizures, or convulsions
- Orthostatic hypotension or serious heart conditions including pulmonary hypertension, obstructive coronary artery disease, hypertrophic cardiomyopathy, myocardial infarction, coronary artery revascularization, heart failure, left ventricular hypertrophy, or moderate to severe heart valve disease
- Currently taking prohibited medications
- Pregnant or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Neurocrine Clinical Site
London, United Kingdom, SE5 8AZ
Actively Recruiting
2
Neurocrine Clinical Site
Oxford, United Kingdom, OX3 7JX
Actively Recruiting
Research Team
N
Neurocrine Medical Information Call Center
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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