Actively Recruiting
Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO)
Led by University of Wisconsin, Madison · Updated on 2025-07-04
75
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the pNANO neurologic exam scale to provide a more objective and standard way to assess tumor response in children with brain and spinal cord tumors. This study focuses on measuring the consistency between different providers when using the pNANO scale during routine clinic visits for pediatric brain and spine tumor patients. During the study, each participant will have neurologic exams performed by two or three separate providers on the same day of their scheduled clinic visit. These providers will independently assess and document neurological functions such as gait, strength, cerebellar function, vision, facial strength, consciousness, eye movements, speech, and swallowing using the pNANO scale. The study includes two visits, with the second visit occurring between one and six months after the first. For up to 20% of participants, telemedicine evaluations will be used, with at least one provider physically present in the clinic and others participating virtually. Participants will undergo neurologic exams by different clinicians who will document their findings without discussing them with each other. Providers will also record the time taken for each exam. The study will assess how consistent the pNANO scores are between observers at both visits and whether telemedicine evaluations are feasible. The research team will also evaluate clinical examinations that may relate to the pNANO scores. Participation lasts through the two clinic visits spaced up to six months apart, with evaluations conducted either in person or via telemedicine.
CONDITIONS
Brief Title
Evaluation of the Neurologic Assessment in Pediatric Neuro-Oncology (pNANO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant is 1 year or older and up to 17 years old
- Must be seen in a pediatric clinic
- Radiographic or histologic confirmation of a brain or spine tumor at the time of initial diagnosis
- Participant or parent/guardian must understand and be willing to sign informed consent
You will not qualify if you...
- None specified
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of initial assessment
Participants undergo neurologic examinations by 2 or 3 different providers during a routine clinic visit to assess neurologic function using the pNANO scale.
1 visit (in-person)
Duration - 1 to 6 months
Participants have a follow-up neurologic examination 1 to 6 months after the initial assessment, completed by 2 or 3 providers either in clinic or via telemedicine to evaluate inter-observer variability and feasibility of the pNANO scale.
1 visit (in-person or telemedicine)
Trial Site Locations
Total: 1 location
1
American Family Children's Hospital
Madison, Wisconsin, United States, 53792
Actively Recruiting
Research Team
C
Cancer Connect
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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