Study to Evaluate New Magnetic Resonance Imaging Techniques in Patients and Healthy Volunteers

What this Trial Is About

Researchers are evaluating multiple new magnetic resonance MR imaging techniques in patients and healthy volunteers to determine their feasibility, image quality, and measurement consistency. This master protocol study aims to identify promising MR methods that may be adopted into clinical practice or further developed in larger research studies. The evaluation includes comparing new approaches with standard procedures, assessing software or hardware updates, and developing new sequences to improve imaging in relevant pathologies. The study includes three types of MR measurement evaluations. Type 1 adds new sequences to routine clinical MR exams in patients, with additional imaging lasting no more than 15 minutes and no extra contrast agents beyond routine care. Type 2 involves complete dedicated MR sessions lasting 30 to 90 minutes to evaluate new techniques during patient treatment, requiring written informed consent. Type 3 includes MR measurements in healthy volunteers to establish technique performance and repeatability, also lasting 30 to 90 minutes with informed consent. No intravenous contrast agents are administered specifically for the study. Participants will undergo MR imaging sessions according to their group, with data collected during routine or additional scans. Patients in Type 1 receive extra sequences during their standard clinical exams. Type 2 patients have scheduled research scans alongside clinical care. Volunteers in Type 3 undergo MR scans for research purposes. The research team will assess feasibility, image quality, and repeatability over a 10-year period, comparing new MR techniques with current methods and evaluating pre- and post-treatment imaging. Consent and safety protocols are followed throughout the study.

Evaluation of New Magnetic Resonance Techniques